公开(公告)号：US20090241214A1

公开(公告)日：2009-09-24

申请号：US12261951

申请日：2008-10-30

申请人： DECHUN WANG ,  CLARICE MENSAH ,  CHRISTINA DIFONZO ,  GUORONG ZHANG ,  MENGHAN LIU ,  ZHENYU YANG

发明人： DECHUN WANG ,  CLARICE MENSAH ,  CHRISTINA DIFONZO ,  GUORONG ZHANG ,  MENGHAN LIU ,  ZHENYU YANG

IPC分类号： A01H1/02 ,  C12N5/04 ,  C12Q1/68

CPC分类号： A01H1/04 ,  A01H5/10 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156

摘要： The present invention relates to compositions and methods for providing and using markers of aphid resistant germplasm, particularly for identifying aphid resistance germplasm in soybean plants. Specifically, the inventions related to providing aphid resistant germplasm identified by markers associated with decreased damage from aphid feeding, as well as enhanced tolerance to aphid infestation of soybean plants. More particularly, the invention relates to compositions and methods for using genetic markers in breeding methods for producing plants with increased resistance to aphid damage and tolerance, while retaining and acquiring desired agronomic traits, Furthermore, the invention relates to plants produced by these breeding programs for use in commercial soybean production.

摘要翻译： 本发明涉及用于提供和使用蚜虫抗性种质的标记物的组合物和方法，特别是用于鉴定大豆植物中的蚜虫抗性种质。 具体而言，涉及提供与由蚜虫喂养减少的损伤相关的标记鉴定的蚜虫抗性种质以及增强对大豆植物蚜虫侵染的耐受性的发明。 更具体地说，本发明涉及在保留和获得所需农学性状的同时，在育种方法中使用遗传标记物来生产对蚜虫损害和耐受性增加的抗性的组合物和方法。此外，本发明涉及通过这些育种程序产生的植物 用于商业大豆生产。

公开(公告)号：US08227662B2

公开(公告)日：2012-07-24

申请号：US12261951

申请日：2008-10-30

申请人： Dechun Wang ,  Clarice Mensah ,  Christina DiFonzo ,  Guorong Zhang ,  Menghan Liu ,  Zhenyu Yang

发明人： Dechun Wang ,  Clarice Mensah ,  Christina DiFonzo ,  Guorong Zhang ,  Menghan Liu ,  Zhenyu Yang

IPC分类号： A01H1/00 ,  A01H1/02 ,  C12Q1/68 ,  C12N5/04

CPC分类号： A01H1/04 ,  A01H5/10 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156

摘要： The present invention relates to compositions and methods for providing and using markers of aphid resistant germplasm, particularly for identifying aphid resistance germplasm in soybean plants. Specifically, the inventions related to providing aphid resistant germplasm identified by markers associated with decreased damage from aphid feeding, as well as enhanced tolerance to aphid infestation of soybean plants. More particularly, the invention relates to compositions and methods for using genetic markers in breeding methods for producing plants with increased resistance to aphid damage and tolerance, while retaining and acquiring desired agronomic traits, Furthermore, the invention relates to plants produced by these breeding programs for use in commercial soybean production.

摘要翻译： 本发明涉及用于提供和使用蚜虫抗性种质的标记物的组合物和方法，特别是用于鉴定大豆植物中的蚜虫抗性种质。 具体而言，涉及提供与由蚜虫喂养减少的损伤相关的标记鉴定的蚜虫抗性种质以及增强对大豆植物蚜虫侵染的耐受性的发明。 更具体地说，本发明涉及在保留和获得所需农学性状的同时，在育种方法中使用遗传标记物来生产对蚜虫损害和耐受性增加的抗性的组合物和方法。此外，本发明涉及通过这些育种程序产生的植物 用于商业大豆生产。

公开(公告)号：US20240139228A1

公开(公告)日：2024-05-02

申请号：US18484291

申请日：2023-10-10

申请人： Alan Y. LU ,  Huanlong QIN ,  Menghan LIU ,  Patrick Y. LU

发明人： Alan Y. LU ,  Huanlong QIN ,  Menghan LIU ,  Patrick Y. LU

IPC分类号： A61K31/7105 ,  A61K47/10 ,  A61K47/42 ,  A61K48/00 ,  A61P35/00

CPC分类号： A61K31/7105 ,  A61K47/10 ,  A61K47/42 ,  A61K48/00 ,  A61P35/00 ,  C12Q2600/178 ,  G01N33/57419

摘要： A pharmaceutical composition, comprises micro RNAs with or without chemical modification, and a carder suitable for delivery in vivo, the carrier is a branched histidine-lysine polypeptide or modified compound thereof. The pharmaceutical composition is capable of inhibiting the growth of colon cancer by inducing programmed death of cancer cell and further be used for the manufacture of a targeted drug for colorectal cancer treatment.