公开(公告)号：US20250025545A1

公开(公告)日：2025-01-23

申请号：US18714854

申请日：2022-12-01

Applicant: Kanagawa Institute of Industrial Science and Technology ,  University of Tsukuba ,  Metagen, Inc.

Inventor： Shinji Fukuda ,  Gaku Nakato ,  Nozomu Obana ,  Risako Furukawa

IPC: A61K39/02 ,  C07K14/195

Abstract: Determination of the mechanism of allergy development in which a bacterium of the family Lachnospiraceae, which is an enteric bacterium, including Ruminococcus gnavus is involved and developing a method for preventing or treating allergies by intervening in the mechanism. Since the Ibp protein from a bacterium of the family Lachnospiraceae is involved in development of allergies, allergic reactions occurring in vivo can be prevented by administration or induction of in vivo production of a substance that binds to the Ibp protein.