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公开(公告)号：US20110275933A1
公开(公告)日：2011-11-10
申请号：US13125608
申请日：2009-10-22
申请人： Joyoni DEY , Michael A. King
发明人： Joyoni DEY , Michael A. King
摘要： The invention relates to methods and systems for compensating for respiratory motion of individuals during nuclear imaging. In some embodiments, the methods include obtaining data representing a reference respiratory state for the individual and obtaining data that represents a plurality of respiratory states that correspond to at least a portion of a cycle of respiration of the individual; comparing each of the plurality of respiratory states to a subset of the reference state data to obtain a motion estimate of each of the plurality of respiratory states; compensating for respiratory motion in each of the plurality of respiratory states based on the motion estimates to obtain motion-compensated respiratory state data; and constructing an image using the motion-compensated respiratory state data.
摘要翻译： 本发明涉及用于在核成像期间补偿个体的呼吸运动的方法和系统。 在一些实施例中，所述方法包括获得表示个体的参考呼吸状态的数据，并且获得表示对应于个人呼吸循环的至少一部分的多个呼吸状态的数据; 将所述多个呼吸状态中的每一个与所述参考状态数据的子集进行比较，以获得所述多个呼吸状态中的每一个的运动估计; 基于所述运动估计来补偿所述多个呼吸状态中的每一个中的呼吸运动，以获得运动补偿呼吸状态数据; 以及使用运动补偿呼吸状态数据构建图像。
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公开(公告)号：US4477834A
公开(公告)日：1984-10-16
申请号：US380610
申请日：1982-05-21
申请人： David A. Beaumont , Michael A. King
发明人： David A. Beaumont , Michael A. King
摘要： A scan conversion circuit for a thermal imager device in which a field is scanned by a parallel-series array of infra-red detectors swept broadside over the field to produce a band of parallel I.R. signals. The signals from the array of detectors are sampled at high speed in a pattern which traces each parallel line of detectors in turn. A C.R.T. is scanned in a similar pattern, the pattern being repeated at high speed with successive lateral displacements corresponding to the rate at which the I.R. array sweeps the field.
摘要翻译： 一种用于热像仪装置的扫描转换电路，其中通过平行串联阵列的红外探测器扫描场，所述红外探测器在所述场上扫过宽边，以产生平行的I.R。 信号。 来自检测器阵列的信号以高速采样，其形式依次跟踪每条平行的检测器线。 一个C.R.T. 以类似的图案扫描，图案以高速重复，连续的横向位移对应于I.R.的速率。 阵列扫描字段。
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公开(公告)号：US5112607A
公开(公告)日：1992-05-12
申请号：US715094
申请日：1991-06-05
申请人： Thomas H. Hudson , Michael A. King
发明人： Thomas H. Hudson , Michael A. King
IPC分类号： A61K39/395 , A61K47/48
CPC分类号： A61K47/48438 , A61K39/395
摘要： A method of potentiating immunotoxin action in an immunotoxin/target-cell stem in which Brefeldin A is utilized as an immunopotentiator. The Brefeldin A enhances the immunotoxin pathway while blocking or inhibiting the nonspecific pathway, thus being particularly useful in conjunction with immunotoxins made from holotoxins. The Brefeldin A is effective in small, nontoxic concentrations and therefore may be utilized with either in vivo or in vitro systems.
摘要翻译： 在其中使用布雷菲德菌素A作为免疫增强剂的免疫毒素/靶细胞系统中增强免疫毒素作用的方法。 布雷菲德菌素A增强免疫毒素途径，同时阻断或抑制非特异性途径，因此特别适用于由全毒素制成的免疫毒素。 布雷菲德菌素A在小的无毒浓度下有效，因此可以与体内或体外系统一起使用。
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4.发明申请SYNCHRONIZATION OF PATIENT MOTION DETECTION EQUIPMENT WITH MEDICAL IMAGING SYSTEMS 审中-公开患者运动检测设备与医学成像系统的同步公开(公告)号：US20150134261A1
公开(公告)日：2015-05-14
申请号：US14080353
申请日：2013-11-14
摘要： An improved system and method to acquire physiological information about a state of a subject, such as SPECT and PET information. The system generates a predetermine sequence of pulse signals and combines that sequence with a first physiological signal to generate a time-base signal. The time-base signal is than combined with a second physiological signal. The combined signals are analyzed to determine accurate temporal synchronization of the first and second physiological signals. The system can be generalized to handle more than two physiological signals. Examples of physiological signals can be for example EKG signals, tomography signals, gross-body motion signals, respiratory motion signals, voluntary motion signals, involuntary motion signals and other signals. The analyzed data can be displayed and/or recorded, and provides physiological information about a state of the subject.
摘要翻译： 用于获取关于受试者状态的生理信息的改进的系统和方法，例如SPECT和PET信息。 该系统产生脉冲信号的预定序列，并将该序列与第一生理信号组合以产生时基信号。 时基信号与第二生理信号组合。 分析组合信号以确定第一和第二生理信号的精确时间同步。 该系统可以被推广以处理两个以上的生理信号。 生理信号的示例可以是例如EKG信号，断层摄影信号，总体运动信号，呼吸运动信号，自愿运动信号，非自愿运动信号和其他信号。 可以显示和/或记录分析的数据，并且提供关于对象的状态的生理信息。
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公开(公告)号：US08755586B2
公开(公告)日：2014-06-17
申请号：US13383584
申请日：2010-06-15
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , A61B6/037 , G06T2211/424
摘要： An image reconstruction method comprises reconstructing an image using an iterative reconstruction method and computing a projection used in the reconstructing by summing ray increments between neighboring planes (P0, P1, P2, . . . ) parallel with a detector face (42) with stationary incremental blurring associated with each ray increment computed based on a distance between the neighboring parallel planes. A non-stationary blurring kernel may also be convolved at a plane closest to the detector face to generate a projection incorporating shift-variant blurring.
摘要翻译： 一种图像重建方法包括使用迭代重建方法来重建图像，并且通过将与平行增量的检测器面（42）平行的相邻平面（P0，P1，P2 ...）之间的射线增量相加来计算重建中使用的投影 基于相邻平行平面之间的距离计算的每个射线增量相关联的模糊。 非平稳的模糊核也可以在最接近检测器面的平面上进行卷积，以生成包含移位变型模糊的投影。
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公开(公告)号：US20120114212A1
公开(公告)日：2012-05-10
申请号：US13383584
申请日：2010-06-15
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , A61B6/037 , G06T2211/424
摘要： An image reconstruction method comprises reconstructing an image using an iterative reconstruction method and computing a projection used in the reconstructing by summing ray increments between neighboring planes (P0, P1, P2, . . . ) parallel with a detector face (42) with stationary incremental blurring associated with each ray increment computed based on a distance between the neighboring parallel planes. A non-stationary blurring kernel may also be convolved at a plane closest to the detector face to generate a projection incorporating shift-variant blurring.
摘要翻译： 一种图像重建方法包括使用迭代重建方法来重建图像，并且通过将与平行增量的检测器面（42）平行的相邻平面（P0，P1，P2 ...）之间的射线增量相加来计算重建中使用的投影 基于相邻平行平面之间的距离计算的每个射线增量相关联的模糊。 非平稳的模糊核也可以在最接近检测器面的平面上进行卷积，以生成包含移位变型模糊的投影。
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公开(公告)号：USD457218S1
公开(公告)日：2002-05-14
申请号：US29138248
申请日：2001-03-09
申请人： Michael A. King
设计人： Michael A. King
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