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公开(公告)号:US20070275369A1
公开(公告)日:2007-11-29
申请号:US10581371
申请日:2004-12-06
申请人: John Groves , Michael Baksh , Michal Jaros
发明人: John Groves , Michael Baksh , Michal Jaros
CPC分类号: G01N33/542 , G01N33/5432
摘要: A method and assay are described for measuring the interaction between a ligand and an analyte. The assay can include a suspension of colloidal particles that are associated with a ligand of interest. The colloidal particles are maintained in the suspension at or near a phase transition state from a condensed phase to a dispersed phase. An analyte to be tested is then added to the suspension. If the analyte binds to the ligand, a phase change occurs to indicate that the binding was successful.
摘要翻译: 描述了用于测量配体和分析物之间的相互作用的方法和测定。 该测定可以包括与感兴趣的配体相关联的胶体颗粒的悬浮液。 胶体颗粒在凝聚相到分散相的过渡态或接近状态下保持在悬浮液中。 然后将待测试的分析物加入到悬浮液中。 如果分析物与配体结合,则发生相变,表明结合是成功的。
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公开(公告)号:US20130040306A1
公开(公告)日:2013-02-14
申请号:US13409557
申请日:2012-03-01
申请人: Darryl J. Bornhop , Michael Baksh , M.G. Finn , Amanda Kussrow
发明人: Darryl J. Bornhop , Michael Baksh , M.G. Finn , Amanda Kussrow
IPC分类号: G01N21/75
CPC分类号: G01N21/45 , G01N2021/4709
摘要: Disclosed are improved optical detection methods comprising multiplexed interferometric detection systems and methods for determining a characteristic property of a sample, together with various applications of the disclosed techniques.
摘要翻译: 公开了包括多路复用干涉检测系统和用于确定样品的特性的方法的改进的光学检测方法,以及所公开技术的各种应用。
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