Detection of Molecular Interactions
    1.
    发明申请
    Detection of Molecular Interactions 有权
    检测分子相互作用

    公开(公告)号:US20070275369A1

    公开(公告)日:2007-11-29

    申请号:US10581371

    申请日:2004-12-06

    IPC分类号: C12Q1/70 C12Q1/00

    CPC分类号: G01N33/542 G01N33/5432

    摘要: A method and assay are described for measuring the interaction between a ligand and an analyte. The assay can include a suspension of colloidal particles that are associated with a ligand of interest. The colloidal particles are maintained in the suspension at or near a phase transition state from a condensed phase to a dispersed phase. An analyte to be tested is then added to the suspension. If the analyte binds to the ligand, a phase change occurs to indicate that the binding was successful.

    摘要翻译: 描述了用于测量配体和分析物之间的相互作用的方法和测定。 该测定可以包括与感兴趣的配体相关联的胶体颗粒的悬浮液。 胶体颗粒在凝聚相到分散相的过渡态或接近状态下保持在悬浮液中。 然后将待测试的分析物加入到悬浮液中。 如果分析物与配体结合,则发生相变,表明结合是成功的。