Abstract:
Optical reader systems and methods for label-independent reading of resonant waveguide (RWG) biosensors operably supported by a microplate as defined herein. The system includes a light source, a spectrometer unit, a beam-forming optical system and a scanning optical system that includes a scanning mirror device, a mirror device driver operably coupled to the scanning mirror device, and an F-theta lens arranged between the microplate and the beam-forming optical system. Some systems use multiple optical beams to scan multiple biosensors at once without having to move the microplate. Asynchronous scanning of multiple beams allows for reducing the number of spectrometer units needed.