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公开(公告)号：US6068981A
公开(公告)日：2000-05-30
申请号：US943639
申请日：1997-10-03
CPC分类号： G01N33/5308 , Y10S436/822 , Y10S514/811 , Y10S514/812 , Y10S514/964 , Y10T436/13
摘要： A method of monitoring a therapeutic regimen in an animal, the method involving a) providing to the animal a therapeutic compound and a detectable compound that passes into the bloodstream, excretory system, or other tissue or body fluid in detectable form; b) after a period of time, following step (a), sufficient for passage of a detectable amount of the detectable compound into the body fluid or tissue, collecting a sample of the fluid or tissue from the animal; and c) measuring or detecting the detectable compound, or a detectable metabolite thereof, in the sample, wherein the detectable compound involves one member of a specific binding pair, and detection is carried out using the second member of the specific binding pair.
摘要翻译： 一种监测动物中治疗方案的方法，所述方法包括：a）向动物提供治疗化合物和可检测化合物，其以可检测的形式进入血流，排泄系统或其他组织或体液; b）在步骤（a）之后一段时间后，足以使可检测量的可检测化合物通过体液或组织，从动物收集流体或组织的样品; 和c）测量或检测样品中可检测化合物或其可检测的代谢物，其中可检测化合物涉及特异性结合对的一个成员，并且使用特异性结合对的第二个成员进行检测。
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2.发明申请Apparatus and Method for Detecting Genetic Mutations and Single Nucleotide Polymorphisms 审中-公开用于检测遗传突变和单核苷酸多态性的装置和方法公开(公告)号：US20080153715A1
公开(公告)日：2008-06-26
申请号：US11861933
申请日：2007-09-26
申请人： Michael G. PAPPAS , Zhuying WANG
发明人： Michael G. PAPPAS , Zhuying WANG
IPC分类号： C40B60/10
CPC分类号： C12Q1/6827 , C12Q2565/519 , C12Q2565/137 , C12Q2563/149
摘要： A method and means of identifying nucleic acid oligomers is disclosed. A sample is split into parts and the parts are flowed through chromatography columns containing nucleic acid oligomer probes bound to a binding medium. Analyte oligomers are transiently hybridized to complementary probe oligomers during chromatography. Detection and analysis of oligomer peaks is used to identify the oligomers contained in the sample.
摘要翻译： 公开了鉴定核酸寡聚体的方法和方法。 将样品分成部分，并将部分流经色谱柱，其中含有与结合介质结合的核酸低聚物探针。 分析物低聚物在色谱过程中与互补探针低聚物瞬时杂交。 寡聚物峰的检测和分析用于鉴定样品中所含的低聚物。
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