公开(公告)号：US07718564B2

公开(公告)日：2010-05-18

申请号：US11434717

申请日：2006-05-16

申请人： Jihad Mohammed Dakka ,  Sabato Miseo ,  Stuart Leon Soled ,  Jose Guadalupe Santiesteban ,  Joseph Ernest Baumgartner ,  Michiel Christian Alexander Van Vliet ,  Roger Arthur Sheldon

发明人： Jihad Mohammed Dakka ,  Sabato Miseo ,  Stuart Leon Soled ,  Jose Guadalupe Santiesteban ,  Joseph Ernest Baumgartner ,  Michiel Christian Alexander Van Vliet ,  Roger Arthur Sheldon

IPC分类号： B01J23/72 ,  B01J23/755 ,  B01J31/00 ,  B01J27/24

CPC分类号： B01J31/2243 ,  B01J23/76 ,  B01J2231/70 ,  B01J2531/16 ,  B01J2531/847 ,  C07C68/00 ,  C07C69/96

摘要： The present invention is related to a hydrocarbon oxidation process. The process comprises bringing one or more hydrocarbons into contact with a source of oxygen in the presence of a radical initiator and a catalyst. The catalyst comprises an organic metal complex located on a catalyst support, and is obtained by partial decomposition of the organic metal complex. For example, the process can be used to produce dimethyl carbonate from dimethoxy methane. The invention is also related to a partially decomposed catalyst that comprises a silica support and an organic metal complex, wherein at least 5% of the organic compound remains in the catalyst. The organic metal complex comprises an organic compound and a metal-based compound wherein the metal is selected from copper, nickel, and combinations thereof. The invention is also related to a process for manufacturing of a catalyst comprising mixing L-arginine, a Cu-based compound, water, and optionally another metal-based compound to form a solution; impregnating the solution onto a silica support to form a catalyst precursor; and partially decomposing the L-arginine to form the catalyst so that at least 5% of L-arginine remains in the catalyst.

摘要翻译： 本发明涉及烃氧化方法。 该方法包括在自由基引发剂和催化剂的存在下使一种或多种烃与氧源接触。 催化剂包含位于催化剂载体上的有机金属络合物，并通过有机金属络合物的部分分解获得。 例如，该方法可用于从二甲氧基甲烷生产碳酸二甲酯。 本发明还涉及包含二氧化硅载体和有机金属络合物的部分分解的催化剂，其中至少5％的有机化合物保留在催化剂中。 有机金属络合物包括有机化合物和金属基化合物，其中金属选自铜，镍及其组合。 本发明还涉及制造催化剂的方法，其包括将L-精氨酸，Cu基化合物，水和任选的其它金属类化合物混合以形成溶液; 将溶液浸渍到二氧化硅载体上以形成催化剂前体; 并部分分解L-精氨酸以形成催化剂，使得至少5％的L-精氨酸保留在催化剂中。

公开(公告)号：US20100036126A1

公开(公告)日：2010-02-11

申请号：US12304557

申请日：2007-06-14

申请人： Michiel Christian Alexander van Vliet ,  Gerardus Johannes Kemperman ,  Marcel Schreuder Goedheijt

发明人： Michiel Christian Alexander van Vliet ,  Gerardus Johannes Kemperman ,  Marcel Schreuder Goedheijt

IPC分类号： C07D241/04 ,  C12P17/12

CPC分类号： C07D241/04 ,  C07D471/14 ,  C12P17/12

摘要： This invention provides for a compound according to Formula (1), wherein R1 is methyl, ethyl, n-propyl, isopropyl, benzyl or 2-haloethyl and the use thereof in a method to prepare (S)-1-methyl-3-phenylpiperazine by enzymatic hydrolysis of the compound, followed by separation and cleavage of the oxalamic groups, whereby the protease of Streptomyces griseus is used as enzyme for the enzymatic hydrolysis.

摘要翻译： 本发明提供式（1）化合物，其中R 1为甲基，乙基，正丙基，异丙基，苄基或2-卤代乙基，以及其用于制备（S）-1-甲基-3- 苯基哌嗪通过酶水解化合物，然后分离和切割草酰胺基团，由此将灰链霉菌的蛋白酶用作酶水解的酶。