公开(公告)号：US20110144207A1

公开(公告)日：2011-06-16

申请号：US13058978

申请日：2009-08-14

申请人： Nandkumar Chodankar ,  Milind Biyani ,  Mohan Muthunarayanan ,  Selvaraju Radhakrishnan ,  Sathish Kumar Santhanampillai ,  Rajendran Paul Nadar ,  Vivekanandan Sundaramurthy ,  Sakthivel Lakshamana Prabu

发明人： Nandkumar Chodankar ,  Milind Biyani ,  Mohan Muthunarayanan ,  Selvaraju Radhakrishnan ,  Sathish Kumar Santhanampillai ,  Rajendran Paul Nadar ,  Vivekanandan Sundaramurthy ,  Sakthivel Lakshamana Prabu

IPC分类号： A61K31/19 ,  C07C63/00 ,  C07C63/04 ,  C07C65/24 ,  C07C229/40 ,  C07D209/26 ,  C07D491/052 ,  C07C63/33 ,  C07C59/185 ,  A61P29/00

CPC分类号： A61K9/2018 ,  A61K9/2054 ,  A61K9/2059 ,  C07C51/412 ,  C07C57/30 ,  C07C59/56 ,  C07C59/64 ,  C07C227/16 ,  C07D209/28 ,  C07C229/42

摘要： The invention particularly discloses a process for preparing aryl alkyl carboxylic acid salts by preparing aqueous alkali solution, adding aryl alkyl carboxylic acid to said alkali solution at a temperature ranging from 4° to 121° C. for obtaining a clear solution, preferably by heating and/or stirring and concentrating and cooling to obtain aryl alkyl carboxylic acid salt The invention therefore discloses solid oral dosage forms and compositions of aryl alkyl carboxylic acid salts which are free of organic solvent/so. The solid oral dose compositions of aryl alkyl carboxylic acid salts of the invention are prepared in situ from aryl alkyl carboxylic acids and bases to obtain aryl acid alkyl carboxylic acid sails in crystalline/powder form with or without the use of pharmaceutical excipients.

摘要翻译： 本发明特别公开了一种制备芳基烷基羧酸盐的方法，通过制备碱水溶液，在4℃至121℃的温度范围内向所述碱溶液中加入芳基烷基羧酸，以获得澄清溶液，优选通过加热和 /或搅拌并浓缩并冷却以获得芳基烷基羧酸盐因此，本发明公开了不含有机溶剂的固体口服剂型和芳基烷基羧酸盐的组合物。 本发明的芳基烷基羧酸盐的固体口服剂量组合物由芳基烷基羧酸和碱原位制备得到具有或不使用药用赋形剂的结晶/粉末形式的芳基烷基羧酸帆。

公开(公告)号：US06361818B1

公开(公告)日：2002-03-26

申请号：US09729356

申请日：2000-12-05

申请人： Milind Kesharlal Biyani ,  Manisha Manohar Banavaliker ,  Geeta Chandravadan Parikh ,  Sushma Milind Biyani

发明人： Milind Kesharlal Biyani ,  Manisha Manohar Banavaliker ,  Geeta Chandravadan Parikh ,  Sushma Milind Biyani

IPC分类号： A23L1212

摘要： Nutrient rich, low fat, high fiber, carrot product containing 20-50% by weight of fiber of which 15-40% by weight is insoluble and 5-10% by weight is soluble, 0.1-1.0% by weight of fat, 10-55% by weight of carbohydrates, 0.02-1% by weight of carotenoids and vitamins and 5-10% by weight of minerals and trace elements. A process for the preparation of the carrot product requires the step of stabilizing carrot juice with carbohydrate in amounts ranging from 1-10% by weight of the juice. A formulation of the carrot product mixed with excipients.