公开(公告)号：US09259450B2

公开(公告)日：2016-02-16

申请号：US13186956

申请日：2011-07-20

Applicant: Ming-Hong Chuang ,  Cheng Der Tony Yu ,  Kung-Ming Lu

Inventor： Ming-Hong Chuang ,  Cheng Der Tony Yu ,  Kung-Ming Lu

IPC: A61K35/00 ,  A61K36/48 ,  A61K31/43

CPC classification number: A61K36/48 ,  A61K31/43 ,  A61K2035/115 ,  A61K2300/00

Abstract: The present invention relates to use of a fermented soy extract as a prebiotic composition to protect beneficial bacteria in the gastrointestinal tract of an animal. Particularly, the fermented soy extract of the invention exhibits the prebiotic activity even under an antibiotic treatment. Also disclosed is combined use of an antibiotic and the fermented soy extract of the invention, which has advantages over administration of the antibiotic alone, such as decreasing the effective dose of the antibiotic and/or reducing side effects resulting from the antibiotic treatment.

Abstract translation: 本发明涉及发酵大豆提取物作为益生元组合物来保护动物胃肠道中的有益细菌的用途。 特别地，本发明的发酵大豆提取物即使在抗生素治疗下也显示益生元活性。 还公开了本发明的抗生素和发酵大豆提取物的组合使用，其具有优于单独使用抗生素的优点，例如降低抗生素的有效剂量和/或减少由抗生素治疗引起的副作用。

公开(公告)号：US20090280062A1

公开(公告)日：2009-11-12

申请号：US12425319

申请日：2009-04-16

Applicant: Chi-Huey Wong ,  Ming-Hong Chuang ,  Wen-Bin Yang ,  Shyh-Horng Chiou

Inventor： Chi-Huey Wong ,  Ming-Hong Chuang ,  Wen-Bin Yang ,  Shyh-Horng Chiou

IPC: A61K49/00 ,  A61K31/715 ,  C12Q1/68 ,  A61K31/19 ,  A61P39/00

CPC classification number: G01N33/5085 ,  A61K36/07 ,  A61K36/074 ,  G01N2333/43534 ,  G01N2333/70596 ,  A61K2300/00

Abstract: A composition of acetic acid and a composition of acetic acid and RF3 effecting expression of DAF-16 in C. elegans, wherein the at least acetic acid and the RF3 polysaccharide is effective to increase the life-span of C. elegans or humans. A method of regulating DAF-16 expression, comprising: administering a composition comprising at least acetic acid and RF3 polysaccharide; providing the composition to at least one receptor on a surface of a cell; causing an increase in expression of DAF-16. A method for screening a series of compounds or constituents parts of compounds including some antioxidant vitamins, traditional herb medicines, and vinegars using C. elegans as a live organism model to examine to determine if they have an impact the lifespan of C. elegans and the underlying mechanism(s) thereof.

Abstract translation: 乙酸组合物和乙酸组合物和RF3在线虫中影响DAF-16的表达，其中至少乙酸和RF3多糖有效地增加秀丽隐杆线虫或人类的寿命。 一种调节DAF-16表达的方法，包括：施用至少包含乙酸和RF3多糖的组合物; 将组合物提供给细胞表面上的至少一种受体; 导致DAF-16的表达增加。 一种用于筛选一系列化合物或组分的化合物的方法，包括一些抗氧化维生素，传统草药和使用秀丽隐杆线虫作为活生物体模型的葡萄，以检查它们是否影响线虫的寿命 其基本机制。

公开(公告)号：US20120058104A1

公开(公告)日：2012-03-08

申请号：US13186956

申请日：2011-07-20

Applicant: MING-HONG CHUANG ,  CHENG DER TONY YU ,  KUNG-MING LU

Inventor： MING-HONG CHUANG ,  CHENG DER TONY YU ,  KUNG-MING LU

IPC: A61K35/00 ,  A61P31/04

CPC classification number: A61K36/48 ,  A61K31/43 ,  A61K2035/115 ,  A61K2300/00

Abstract: The present invention relates to use of a fermented soy extract as a prebiotic composition to protect beneficial bacteria in the gastrointestinal tract of an animal. Particularly, the fermented soy extract of the invention exhibits the prebiotic activity even under an antibiotic treatment. Also disclosed is combined use of an antibiotic and the fermented soy extract of the invention, which has advantages over administration of the antibiotic alone, such as decreasing the effective dose of the antibiotic and/or reducing side effects resulting from the antibiotic treatment.

Abstract translation: 本发明涉及发酵大豆提取物作为益生元组合物来保护动物胃肠道中的有益细菌的用途。 特别地，本发明的发酵大豆提取物即使在抗生素治疗下也显示益生元活性。 还公开了本发明的抗生素和发酵大豆提取物的组合使用，其具有优于单独使用抗生素的优点，例如降低抗生素的有效剂量和/或减少由抗生素治疗引起的副作用。