公开(公告)号：US4368185A

公开(公告)日：1983-01-11

申请号：US198581

申请日：1980-10-20

申请人： Mitsuo Mizuno ,  Akinori Suginaka ,  Masahiko Fujii ,  Shinichi Akimoto

发明人： Mitsuo Mizuno ,  Akinori Suginaka ,  Masahiko Fujii ,  Shinichi Akimoto

IPC分类号： A61K9/02 ,  A61K31/75 ,  A61K31/765 ,  A61K47/00

CPC分类号： A61K9/02 ,  Y10S424/15

摘要： A suppository base composition comprising 5-80% by weight of polyethylene glycol, 5-80% by weight of triglyceride of fatty acid having 6-22 carbon atoms and 5-80% by weight of a specifically limited alkylene oxide derivative has a melting point of 30.degree.-60.degree. C., a compatibility with both of a polar drug component and a non-polar drug component, and can provide suppositories having excellent moldability and storage stability.

摘要翻译： 包含5-80重量％的聚乙二醇，5-80重量％的具有6-22个碳原子的脂肪酸的甘油三酯和5-80重量％的特异性有限的环氧烷衍生物的栓剂基础组合物具有熔点 30℃〜60℃，与极性药物成分和非极性药物成分的相溶性，能够提供成型性和保存稳定性优异的栓剂。

公开(公告)号：US4770279A

公开(公告)日：1988-09-13

申请号：US30501

申请日：1987-03-27

申请人： Takeshi Shiozaki ,  Yutaka Tokizane ,  Mitsuo Mizuno

发明人： Takeshi Shiozaki ,  Yutaka Tokizane ,  Mitsuo Mizuno

IPC分类号： F16D41/06 ,  F16D41/067

CPC分类号： F16D41/067

摘要： A one-way clutch that employs spaced apart magnetic members to draw rollers into portions of a cam surface so that a shaft and race will rotate as one.

摘要翻译： 一种单向离合器，其采用间隔开的磁性构件将辊子拉入凸轮表面的一部分，使得轴和座圈将一个旋转。

公开(公告)号：US4462984A

公开(公告)日：1984-07-31

申请号：US425101

申请日：1982-09-27

申请人： Mitsuo Mizuno ,  Akinori Suginaka ,  Masahiko Fujii ,  Shinichi Akimoto

发明人： Mitsuo Mizuno ,  Akinori Suginaka ,  Masahiko Fujii ,  Shinichi Akimoto

IPC分类号： A61K9/02

CPC分类号： A61K9/02 ,  Y10S424/15

摘要： A suppository base composition comprising 5-80% by weight of polyethylene glycol, 5-80% by weight of triglyceride of fatty acid having 6-22 carbon atoms and 5-80% by weight of a specifically limited alkylene oxide derivative has a melting point of 30.degree.-60.degree. C., a compatibility with both of a polar drug component and a non-polar drug component, and can provide suppositories having excellent moldability and storage stability.

摘要翻译： 包含5-80重量％的聚乙二醇，5-80重量％的具有6-22个碳原子的脂肪酸的甘油三酯和5-80重量％的特异性有限的环氧烷衍生物的栓剂基础组合物具有熔点 30℃〜60℃，与极性药物成分和非极性药物成分的相溶性，能够提供成型性和保存稳定性优异的栓剂。