Targeting drug/gene carriers to irradiated tissue
    1.
    发明授权
    Targeting drug/gene carriers to irradiated tissue 失效
    将药物/基因载体靶向辐照的组织

    公开(公告)号:US07182933B2

    公开(公告)日:2007-02-27

    申请号:US09975899

    申请日:2001-10-12

    IPC分类号: A61K49/00 A61K39/395 A61K9/27

    摘要: The present invention provides a biomolecular carrier of pharmaceuticals, comprising: a biomolecule carrier bearing molecules that bind to a cellular adhesion molecule expressed on endothelial cell; and a pharmaceutical. The present invention also provides a method of treating a pathophysiological state in an individual in need of such treatment, comprising the steps of: irradiating a target tissue or organ in said individual; and administering to said individual the biomolecular carrier disclosed herein.

    摘要翻译: 本发明提供了一种药物的生物分子载体,其包含:携带分子的生物分子载体,其结合在内皮细胞上表达的细胞粘附分子; 和制药。 本发明还提供一种治疗需要这种治疗的个体的病理生理状态的方法,包括以下步骤:照射所述个体中的靶组织或器官; 并向所述个体施用本文公开的生物分子载体。