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公开(公告)号:US07182933B2
公开(公告)日:2007-02-27
申请号:US09975899
申请日:2001-10-12
IPC分类号: A61K49/00 , A61K39/395 , A61K9/27
CPC分类号: A61K9/5153 , A61K47/6843 , A61K47/6849 , A61K2039/505 , C07K16/18 , C07K16/2821
摘要: The present invention provides a biomolecular carrier of pharmaceuticals, comprising: a biomolecule carrier bearing molecules that bind to a cellular adhesion molecule expressed on endothelial cell; and a pharmaceutical. The present invention also provides a method of treating a pathophysiological state in an individual in need of such treatment, comprising the steps of: irradiating a target tissue or organ in said individual; and administering to said individual the biomolecular carrier disclosed herein.
摘要翻译: 本发明提供了一种药物的生物分子载体,其包含:携带分子的生物分子载体,其结合在内皮细胞上表达的细胞粘附分子; 和制药。 本发明还提供一种治疗需要这种治疗的个体的病理生理状态的方法,包括以下步骤:照射所述个体中的靶组织或器官; 并向所述个体施用本文公开的生物分子载体。