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    Mutant luciferases
    2.
    发明授权
    Mutant luciferases 失效

    公开(公告)号：US06552179B1

    公开(公告)日：2003-04-22

    申请号：US08478205

    申请日：1995-06-07

    申请人： Keith V. Wood ,  Monika G. Gruber

    发明人： Keith V. Wood ,  Monika G. Gruber

    IPC分类号： C12N1553

    CPC分类号： C12N9/0069 ,  C12Y113/12007

    摘要： The invention provides active, non-naturally occurring mutants of beetle luciferases and DNAs which encode such mutants. A mutant luciferase of the invention differs from the corresponding wild-type luciferase by producing bioluminescence with a wavelength of peak intensity that differs by at least 1 nm from the wavelength of peak intensity of the bioluminescence produced by the wild-type enzyme. The mutant luciferases and DNAs of the invention are employed in various biosensing applications.

    Mutant luciferases
    3.
    发明授权
    Mutant luciferases 失效
    突变荧光素酶

    公开(公告)号：US06387675B1

    公开(公告)日：2002-05-14

    申请号：US08487183

    申请日：1995-06-07

    申请人： Keith V. Wood ,  Monika G. Gruber

    发明人： Keith V. Wood ,  Monika G. Gruber

    IPC分类号： C12N902

    CPC分类号： C12N9/0069 ,  C12Y113/12007

    摘要： The invention provides active, non-naturally occurring mutants of beetle luciferases and DNAs which encode such mutants. A mutant luciferase of the invention differs from the corresponding wild-type luciferase by producing bioluminescence with a wavelength of peak intensity that differs by at least 1 nm from the wavelength of peak intensity of the bioluminescence produced by the wild-type enzyme. The mutant luciferases and DNAs of the invention are employed in various biosensing applications.

    摘要翻译： 本发明提供活性的非天然存在的甲虫荧光素酶突变体和编码这种突变体的DNA。 本发明的突变荧光素酶与相应的野生型荧光素酶不同，是通过产生与由野生型酶产生的生物发光的峰值强度相差至少1nm的峰强度波长的生物发光。 本发明的突变荧光素酶和DNA用于各种生物感测应用中。