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公开(公告)号:US08337850B2
公开(公告)日:2012-12-25
申请号:US13228532
申请日:2011-09-09
Applicant: Bianca Ahrens , Sangita M. Baxi , Timothy Scott Fisher , Richard Michael Jerome , Kathrin Ladetzki-Baehs , Theodore Oliphant , Leslie Lynne Sharp , Michael Tesar , Libbey Anne Yates , Moritz Zulley
Inventor: Bianca Ahrens , Sangita M. Baxi , Timothy Scott Fisher , Richard Michael Jerome , Kathrin Ladetzki-Baehs , Theodore Oliphant , Leslie Lynne Sharp , Michael Tesar , Libbey Anne Yates , Moritz Zulley
IPC: A61K39/395 , C07K16/28 , C12P21/02
CPC classification number: C07K16/2878 , A61K38/02 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2887 , C07K16/30 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/74 , C07K2317/75 , C07K2317/92 , C12N5/06 , C12N15/62
Abstract: The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
Abstract translation: 本公开提供了结合人4-1BB的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,药物组合物 含有结合分子的方法和使用结合分子或组合物的方法。
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公开(公告)号:US20120237498A1
公开(公告)日:2012-09-20
申请号:US13228532
申请日:2011-09-09
Applicant: Bianca AHRENS , Sangita M. BAXI , Timothy Scott FISHER , Richard Michael JEROME , Kathrin LADETZKI-BAEHS , Theodore OLIPHANT , Leslie Lynne SHARP , Michael TESAR , Libbey Anne YATES , Moritz ZULLEY
Inventor: Bianca AHRENS , Sangita M. BAXI , Timothy Scott FISHER , Richard Michael JEROME , Kathrin LADETZKI-BAEHS , Theodore OLIPHANT , Leslie Lynne SHARP , Michael TESAR , Libbey Anne YATES , Moritz ZULLEY
IPC: A61K39/395 , C07K16/00
CPC classification number: C07K16/2878 , A61K38/02 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2887 , C07K16/30 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/74 , C07K2317/75 , C07K2317/92 , C12N5/06 , C12N15/62
Abstract: The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.
Abstract translation: 本公开提供了结合人4-1BB的分离的结合分子,编码结合分子的氨基酸序列的核酸分子,包含核酸分子的载体,含有载体的宿主细胞,制备结合分子的方法,药物组合物 含有结合分子的方法和使用结合分子或组合物的方法。
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