COMPOSITION FOR THE PREVENTION AND TREATMENT OF ALOPECIA, OR FOR HAIR GROWTH
    1.
    发明申请
    COMPOSITION FOR THE PREVENTION AND TREATMENT OF ALOPECIA, OR FOR HAIR GROWTH 有权
    用于预防和治疗阿尔卑斯,或用于头发生长的组合物

    公开(公告)号:US20120004439A1

    公开(公告)日:2012-01-05

    申请号:US13057646

    申请日:2009-07-30

    IPC分类号: C07F9/09

    CPC分类号: A61Q7/00 A61K8/553 A61K8/68

    摘要: Disclosed is a composition for prevention and treatment of alopecia or for hair growth, comprising a phytosphingosine-1-phosphate derivative or a pharmaceutically acceptable salt thereof as an active ingredient. Also, a medicine comprising the composition and a quasi-drug comprising the composition are provided.

    摘要翻译: 公开了用于预防和治疗脱发或毛发生长的组合物,其包含植物鞘氨醇-1-磷酸酯衍生物或其药学上可接受的盐作为活性成分。 此外,提供了包含该组合物的药物和包含该组合物的准药物。

    Composition for the prevention and treatment of alopecia, or for hair growth
    2.
    发明授权
    Composition for the prevention and treatment of alopecia, or for hair growth 有权
    用于预防和治疗脱发或头发生长的组合物

    公开(公告)号:US08729052B2

    公开(公告)日:2014-05-20

    申请号:US13057646

    申请日:2009-07-30

    IPC分类号: A01N65/00

    CPC分类号: A61Q7/00 A61K8/553 A61K8/68

    摘要: Disclosed is a composition for prevention and treatment of alopecia or for hair growth, comprising a phytosphingosine-1-phosphate derivative or a pharmaceutically acceptable salt thereof as an active ingredient. Also, a medicine comprising the composition and a quasi-drug comprising the composition are provided.

    摘要翻译: 公开了用于预防和治疗脱发或毛发生长的组合物,其包含植物鞘氨醇-1-磷酸酯衍生物或其药学上可接受的盐作为活性成分。 此外,提供了包含该组合物的药物和包含该组合物的准药物。

    Liposomes comprising peptide antigens derived from X protein of hepatitis B virus
    3.
    发明授权
    Liposomes comprising peptide antigens derived from X protein of hepatitis B virus 失效
    脂质体包含衍生自乙型肝炎病毒X蛋白的肽抗原

    公开(公告)号:US06380359B1

    公开(公告)日:2002-04-30

    申请号:US09051006

    申请日:1998-03-30

    IPC分类号: C07K100

    摘要: The present invention relates to liposomes comprising novel peptide antigens which play a role in regulating human immunity against hepatitis B virus, more specifically, to peptide groups corresponding to epitopes of antigens derived from X protein of HBV which induce cytotoxic T lymphocytes against the virus or immunological tolerance to the virus, and pH-sensitive liposomes comprising said peptide groups to induce cellular immunity so that CTLs specific to the virus can be produced. Since peptide antigens derived from X protein such as X3, X4, X5, X6 and X7 activate CTL which can recognize HBV antigens present in human body, and can also be recognized by the CTL, the liposomes can be used for the development of proposed therapeutic agents for the prevention and treatment of HBV-associated diseases.

    摘要翻译: 本发明涉及包含新型肽抗原的新型肽抗原,其在调节人乙型肝炎病毒的免疫力方面发挥作用,更具体地说,涉及对应于来自HBV的X蛋白的抗原表位的肽组,所述抗原蛋白诱导针对病毒的细胞毒性T淋巴细胞或免疫学 对病毒的耐受性和包含所述肽基团的pH敏感性脂质体以诱导细胞免疫,从而可以产生对病毒特异性的CTL。 由于衍生自X蛋白(例如X 3,X 4,X 5,X 6和X 7)的肽抗原活化能够识别存在于人体中的HBV抗原的CTL,并且也可被CTL识别,脂质体可用于开发所提出的治疗 用于预防和治疗HBV相关疾病的药物。