公开(公告)号：US20230046820A1

公开(公告)日：2023-02-16

申请号：US17798554

申请日：2021-02-10

Applicant: NANOVISION BIOSCIENCES, INC. ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Abraham Akinin ,  Gert Cauwenberghs ,  Chul Kim ,  Patrick Mercier ,  Hiren Thacker

IPC: A61N1/378 ,  A61N1/02 ,  A61N1/372 ,  A61N1/36

Abstract: Apparatuses and methods are disclosed for efficient wireless powering of an electrical load with precise external control over pulsed voltage waveform and metering of charge delivered. The system interfaces to an inductive coil for RF power delivery from an external duty-cycled RF power transmitter, and the electrical load. The electrical load may be a photosensitive array of electrodes for an optically addressed, electrically activated retinal prosthesis. The voltage waveform to activate the load is controlled by the transmitted RF amplitude, including switching between cathodic and anodic phases of electrical stimulation. Charge delivered to the load is quantified as discharge events through a series capacitor, transmitted by backtelemetry to the receiver for continuous monitoring throughout the stimulation phases. The subject disclosure further provides for calibration of voltage amplitude and charge metering, to compensate for variable wireless link and load conditions, through additional stimulation phases with a supplementary load with known and stable characteristics.

公开(公告)号：US20210121685A1

公开(公告)日：2021-04-29

申请号：US17080779

申请日：2020-10-26

Applicant: Nanovision Biosciences, Inc.

Inventor： Samir Damle ,  Yu-Hsin Liu ,  Nicholas W. Oesch ,  Yu-Hwa Lo

IPC: A61N1/05 ,  A61N1/36 ,  A61N1/08

Abstract: Optoelectronic retinal prostheses transduce light into electrical current for neural stimulation. A novel optoelectronic pixel architecture is presented comprising a vertically integrated photo junction field-effect-transistor (Photo-JFET) and neural stimulating electrode. Experimental measurements demonstrate that optically addressed Photo-JFET pixels utilize phototransistive gain to produce a broad range of neural stimulation current and can effectively stimulate retinal neurons in vitro. The compact nature of the Photo-JFET pixel can enable high resolution retinal prostheses with a theoretical visual acuity ˜20/60 to help restore vision in patients with degenerative retinal diseases.

公开(公告)号：US20220384672A1

公开(公告)日：2022-12-01

申请号：US17829266

申请日：2022-05-31

Applicant: NANOVISION BIOSCIENCES, INC. ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Yu-Hwa Lo ,  Yu-Hsin Liu ,  Hiren D. Thacker

IPC: H01L31/107 ,  G01J1/44 ,  G01S17/88

Abstract: High speed, and high timing resolution photon detecting systems and methods are presented with multiplication and self-quenching and self-recovering functions.

公开(公告)号：US20220387786A1

公开(公告)日：2022-12-08

申请号：US17833843

申请日：2022-06-06

Applicant: NANOVISION BIOSCIENCES, INC. ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Yu-Hsin Liu ,  Yu-Hwa Lo ,  Hiren D. Thacker ,  Nicholas Oesch

IPC: A61N1/05

Abstract: Retinal prostheses are described with visual acuity better than 20/150, and higher sensitivity, dynamic range, and FOV than the state-of-the-art. At least two different techniques are presented, the first being an optically-switched vertical single-transistor amplifier for ultrahigh photocurrent amplification, and the second being nanopatterned pillar electrodes.