公开(公告)号：US20200276255A1

公开(公告)日：2020-09-03

申请号：US16803968

申请日：2020-02-27

Applicant: NINE B CO., LTD. ,  AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Seon-Yong JEONG ,  Eunkuk PARK

IPC: A61K36/185 ,  A61K36/40 ,  A61P5/30

Abstract: The present invention provides a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including extract of Ribes fasciculatum leaves as an active ingredient, and a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including an extract of Cornus officinalis and extract of Ribes fasciculatum leaves as active ingredients.

公开(公告)号：US11464817B2

公开(公告)日：2022-10-11

申请号：US16803968

申请日：2020-02-27

Applicant: NINE B CO., LTD.

Inventor： Seon-Yong Jeong ,  Eunkuk Park

IPC: A61K36/185 ,  A61P5/30 ,  A61K36/40

Abstract: The present invention provides a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including extract of Ribes fasciculatum leaves as an active ingredient, and a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including an extract of Cornus officinalis and extract of Ribes fasciculatum leaves as active ingredients.

公开(公告)号：US11116781B2

公开(公告)日：2021-09-14

申请号：US16069522

申请日：2017-01-13

Applicant: NINE B CO., LTD.

Inventor： Seon-Yong Jeong ,  Eun Kuk Park ,  Mun-Chang Kim ,  Jeong Hyun Kim

IPC: A61K31/7048 ,  A61P5/30 ,  A23L33/10 ,  A61K36/56

Abstract: A pharmaceutical composition for preventing or treating female climacteric syndromes comprising Loganin which increases the concentration of estradiol (17β-estradiol, E2) in the blood of a menopausal mouse model and has shown efficacies such as an increase in the estrogen receptor alpha expression in the uterus, which remedies uterine contraction and degeneration, and decreases in the accumulation and the size of adipocytes in liver and the abdominal adipose tissues and the liver and weight loss, a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient.

公开(公告)号：US20190000869A1

公开(公告)日：2019-01-03

申请号：US16069522

申请日：2017-01-13

Applicant: NINE B CO., LTD.

Inventor： Seon-Yong JEONG ,  Eun Kuk PARK ,  Mun-Chang KIM ,  Jeong Hyun KIM

IPC: A61K31/7048 ,  A23L33/10 ,  A61P5/30

Abstract: A pharmaceutical composition for preventing or treating female climacteric syndromes comprising Loganin which increases the concentration of estradiol (17β-estradiol, E2) in the blood of a menopausal mouse model and has shown efficacies such as an increase in the estrogen receptor alpha expression in the uterus, which remedies uterine contraction and degeneration, and decreases in the accumulation and the size of adipocytes in liver and the abdominal adipose tissues and the liver and weight loss, a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient.