公开(公告)号：US07718367B2

公开(公告)日：2010-05-18

申请号：US11378598

申请日：2006-03-17

Applicant: Yuk-Ming Dennis Lo ,  Rossa Wai Kwun Chiu ,  Stephen Siu Chung Chim ,  Nancy Bo Yin Tsui

Inventor： Yuk-Ming Dennis Lo ,  Rossa Wai Kwun Chiu ,  Stephen Siu Chung Chim ,  Nancy Bo Yin Tsui

IPC: C07H21/04 ,  C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/16

Abstract: Methods and kits are provided for diagnosing, monitoring, or predicting preeclaimpsia in a pregnant woman, trisomy 18 and trisomy 21 in a fetus, as well as for detecting pregnancy in a woman, by quantitatively measuring in the maternal blood the amount of one or more RNA species derived from a set of genetic loci and comparing the amount of the RNA species with a standard control.

Abstract translation: 提供了方法和试剂盒，用于诊断，监测或预测孕妇，18岁的三体性和胎儿中的21三体，以及通过在母亲血液中定量测量一个或多个胎儿的数量，在胎儿中检测怀孕。 衍生自一组遗传基因座的RNA物种，并将RNA物质的量与标准对照进行比较。

公开(公告)号：US20100267034A1

公开(公告)日：2010-10-21

申请号：US12754450

申请日：2010-04-05

Applicant: Yuk-Ming Dennis LO ,  Rossa Wai Kwun CHIU ,  Stephen Siu Chung CHIM ,  Nancy Bo Yin TSUI

Inventor： Yuk-Ming Dennis LO ,  Rossa Wai Kwun CHIU ,  Stephen Siu Chung CHIM ,  Nancy Bo Yin TSUI

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/16

Abstract: Methods and kits are provided for diagnosing, monitoring, or predicting preeclaimpsia in a pregnant woman, trisomy 18 and trisomy 21 in a fetus, as well as for detecting pregnancy in a woman, by quantitatively measuring in the maternal blood the amount of one or more RNA species derived from a set of genetic loci and comparing the amount of the RNA species with a standard control.

Abstract translation: 提供了方法和试剂盒，用于诊断，监测或预测孕妇，18岁的三体性和胎儿中的21三体，以及通过在母亲血液中定量测量一个或多个胎儿的数量，在胎儿中检测怀孕。 来自一组遗传基因座的RNA物种，并将RNA物质的量与标准对照进行比较。