公开(公告)号：US20060154940A1

公开(公告)日：2006-07-13

申请号：US11331372

申请日：2006-01-12

申请人： Tawfik Gharbaoui ,  Dipanjan Sengupta ,  Edward Lally ,  Naomi Kato ,  Marlon Carlos ,  Natalie Rodriguez

发明人： Tawfik Gharbaoui ,  Dipanjan Sengupta ,  Edward Lally ,  Naomi Kato ,  Marlon Carlos ,  Natalie Rodriguez

IPC分类号： A61K31/519 ,  C07D487/02

CPC分类号： C07D487/04

摘要： The present invention relates to processes for preparing pyrazolo[3,4-d]pyrimidine ether compounds that are modulators of glucose metabolism and therefore useful in the treatment of metabolic disorders such as diabetes and obesity.

摘要翻译： 本发明涉及制备作为葡萄糖代谢调节剂的吡唑并[3,4-d]嘧啶醚化合物的方法，因此可用于治疗代谢性疾病如糖尿病和肥胖症。

公开(公告)号：US08983780B2

公开(公告)日：2015-03-17

申请号：US13391272

申请日：2010-08-11

申请人： Naomi Kato ,  Hidetaka Senga ,  Hiroyoshi Suzuki ,  Muneo Yoshie ,  Isamu Fujita ,  Yoshitaka Matsuzaki ,  Toshinari Tanaka

发明人： Naomi Kato ,  Hidetaka Senga ,  Hiroyoshi Suzuki ,  Muneo Yoshie ,  Isamu Fujita ,  Yoshitaka Matsuzaki ,  Toshinari Tanaka

IPC分类号： G01W1/00 ,  B63B35/00 ,  B63B22/18 ,  B63H9/06 ,  G01C13/00 ,  G06F11/30

CPC分类号： B63B35/00 ,  B63B22/18 ,  B63B2035/007 ,  B63H9/06 ,  G01C13/00

摘要： An unmanned drifting substance monitoring buoy (10) is thrown into a water area where a drifting substance is present, thereby tracking and monitoring the drifting substance. The unmanned drifting substance monitoring buoy (10) detects, by a detecting section, a relative location of the drifting substance on the water surface with respect to the unmanned drifting substance monitoring buoy (10), and measures, by a measuring section, directions and strengths of a wind and a tidal current. Then, the unmanned drifting substance monitoring buoy (10) tracks the drifting substance by adjusting, based on the relative location of the drifting substance detected by the detecting section and on the directions and the strengths of the wind and the tidal current measured by the measuring section, a surface area and a direction of a sail (13) by an adjusting section. This achieves an unmanned drifting substance monitoring buoy capable of tracking a drifting substance with small energy even when not only a tidal current but also a flow caused by a wind at the sea surface is large.

摘要翻译： 将无人漂移物质监测浮标（10）投入到存在漂移物质的水域中，从而跟踪和监测漂移物质。 无人漂移物质监测浮标（10）通过检测部分检测漂移物质相对于无人漂移物质监测浮标（10）在水面上的相对位置，并由测量部分测量方向和 强风和潮流。 然后，无人漂移物质监测浮标（10）通过根据检测部分检测到的漂移物质的相对位置和风向的方向和强度以及通过测量测量的潮汐电流进行调整来跟踪漂移物质 横截面，表面积和帆的方向（13）。 即使不仅潮汐流而且由于海面的风引起的流量大，所以能够实现能够以小能量跟踪漂移物质的无人漂移物质监测浮标。

公开(公告)号：US20120158303A1

公开(公告)日：2012-06-21

申请号：US13391272

申请日：2010-08-11

申请人： Naomi Kato ,  Hidetaka Senga ,  Hiroyoshi Suzuki ,  Muneo Yoshie ,  Isamu Fujita ,  Yoshitaka Matsuzaki ,  Toshinari Tanaka

发明人： Naomi Kato ,  Hidetaka Senga ,  Hiroyoshi Suzuki ,  Muneo Yoshie ,  Isamu Fujita ,  Yoshitaka Matsuzaki ,  Toshinari Tanaka

IPC分类号： G06F19/00 ,  B63H9/04 ,  B63B35/44 ,  G05D1/02

CPC分类号： B63B35/00 ,  B63B22/18 ,  B63B2035/007 ,  B63H9/06 ,  G01C13/00

摘要： An unmanned drifting substance monitoring buoy (10) is thrown into a water area where a drifting substance is present, thereby tracking and monitoring the drifting substance. The unmanned drifting substance monitoring buoy (10) detects, by a detecting section, a relative location of the drifting substance on the water surface with respect to the unmanned drifting substance monitoring buoy (10), and measures, by a measuring section, directions and strengths of a wind and a tidal current. Then, the unmanned drifting substance monitoring buoy (10) tracks the drifting substance by adjusting, based on the relative location of the drifting substance detected by the detecting section and on the directions and the strengths of the wind and the tidal current measured by the measuring section, a surface area and a direction of a sail (13) by an adjusting section. This achieves an unmanned drifting substance monitoring buoy capable of tracking a drifting substance with small energy even when not only a tidal current but also a flow caused by a wind at the sea surface is large.

摘要翻译： 将无人漂移物质监测浮标（10）投入到存在漂移物质的水域中，从而跟踪和监测漂移物质。 无人漂移物质监测浮标（10）通过检测部分检测漂移物质相对于无人漂移物质监测浮标（10）在水面上的相对位置，并由测量部分测量方向和 强风和潮流。 然后，无人漂移物质监测浮标（10）通过根据检测部分检测到的漂移物质的相对位置和风向的方向和强度以及通过测量测量的潮汐电流进行调整来跟踪漂移物质 横截面，表面积和帆的方向（13）。 即使不仅潮汐流而且由于海面的风引起的流量大，所以能够实现能够以小能量跟踪漂移物质的无人漂移物质监测浮标。

公开(公告)号：US20060155129A1

公开(公告)日：2006-07-13

申请号：US11327923

申请日：2006-01-09

申请人： Tawfik Gharbaoui ,  John Fritch ,  Ashwin Krishnan ,  Beverly Throop ,  Naomi Kato

发明人： Tawfik Gharbaoui ,  John Fritch ,  Ashwin Krishnan ,  Beverly Throop ,  Naomi Kato

IPC分类号： A61K31/513 ,  C07D401/02 ,  C07D403/02

CPC分类号： C07D401/12

摘要： The present invention relates to processes for preparing aromatic ether compounds that are modulators of glucose metabolism and therefore useful in the treatment of metabolic disorders such as diabetes and obesity.

摘要翻译： 本发明涉及制备作为葡萄糖代谢调节剂的芳族醚化合物的方法，因此可用于治疗诸如糖尿病和肥胖症的代谢疾病。