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公开(公告)号：US20080274056A1
公开(公告)日：2008-11-06
申请号：US12043063
申请日：2008-03-05
CPC分类号： A61K9/1075 , A61K9/127 , A61K38/1767 , A61K47/546 , A61K47/62 , A61K47/6907 , A61K47/6911
摘要： Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
摘要翻译： 描述了包含用于递送膜整合肽的纳米颗粒的乳液的组合物。 纳米颗粒包含涂覆有含有膜整合肽的脂质/表面活性剂层的液体疏水核心。 还描述了使用这种组合物的方法。
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公开(公告)号：US08496945B2
公开(公告)日：2013-07-30
申请号：US13109873
申请日：2011-05-17
CPC分类号： A61K9/1075 , A61K9/127 , A61K38/1767 , A61K47/546 , A61K47/62 , A61K47/6907 , A61K47/6911
摘要： Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
摘要翻译： 描述了包含用于递送膜整合肽的纳米颗粒的乳液的组合物。 纳米颗粒包含涂覆有含有膜整合肽的脂质/表面活性剂层的液体疏水核心。 还描述了使用这种组合物的方法。
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公开(公告)号：US20120128590A1
公开(公告)日：2012-05-24
申请号：US13109873
申请日：2011-05-17
CPC分类号： A61K9/1075 , A61K9/127 , A61K38/1767 , A61K47/546 , A61K47/62 , A61K47/6907 , A61K47/6911
摘要： Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
摘要翻译： 描述了包含用于递送膜整合肽的纳米颗粒的乳液的组合物。 纳米颗粒包含涂覆有含有膜整合肽的脂质/表面活性剂层的液体疏水核心。 还描述了使用这种组合物的方法。
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4.发明授权Nanoparticle delivery systems comprising a hydrophobic core and a lipid/surfactant layer comprising a membrane-lytic peptide 有权纳米颗粒递送系统包括疏水核心和包含膜溶解肽的脂质/表面活性剂层公开(公告)号：US07943168B2
公开(公告)日：2011-05-17
申请号：US12043063
申请日：2008-03-05
CPC分类号： A61K9/1075 , A61K9/127 , A61K38/1767 , A61K47/546 , A61K47/62 , A61K47/6907 , A61K47/6911
摘要： Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
摘要翻译： 描述了包含用于递送膜整合肽的纳米颗粒的乳液的组合物。 纳米颗粒包含涂覆有含有膜整合肽的脂质/表面活性剂层的液体疏水核心。 还描述了使用这种组合物的方法。
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