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公开(公告)号：US09539366B2
公开(公告)日：2017-01-10
申请号：US13174311
申请日：2011-06-30
IPC分类号： A61L27/52
CPC分类号： A61L27/52 , A61L2430/02
摘要： It is intended to provide a medical material which enables a new method for cartilage tissue regeneration treatment based on an entirely new concept unlike a treatment method by transplantation of autologous cartilage tissue, a cartilage alternative or undifferentiated cells. The invention provides a bone filler for cartilage tissue regeneration comprising hydrogel having an interpenetrating network structure formed by two or more crosslinked network polymers or a semi-interpenetrating network structure formed by a crosslinked network polymer and a linear polymer. By filling the bone filler of the invention in a hole or a groove provided in subchondral bone just under damaged cartilage tissue, regeneration of the cartilage tissue or both the cartilage tissue and the subchondral bone can be promoted.
摘要翻译： 旨在提供一种医疗材料，其能够通过移植自体软骨组织，软骨替代或未分化细胞而不同于通过移植自体软骨组织的治疗方法，基于全新的概念实现软骨组织再生治疗的新方法。 本发明提供了一种用于软骨组织再生的骨填料，其包括具有由两个或更多个交联网状聚合物形成的互穿网络结构的水凝胶或由交联网状聚合物和线性聚合物形成的半互穿网络结构。 通过将本发明的骨填充物填充在刚好在受损的软骨组织下方的软骨下骨中的孔或槽中，可以促进软骨组织或软骨组织和软骨下骨两者的再生。
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2.发明申请Method for Bone-filling Cartilage Tissue for Inducing Regeneration of the Cartilage 审中-公开骨软骨组织诱导软骨再生的方法公开(公告)号：US20110257763A1
公开(公告)日：2011-10-20
申请号：US13174311
申请日：2011-06-30
IPC分类号： A61F2/02
CPC分类号： A61L27/52 , A61L2430/02
摘要： It is intended to provide a medical material which enables a new method for cartilage tissue regeneration treatment based on an entirely new concept unlike a treatment method by transplantation of autologous cartilage tissue, a cartilage alternative or undifferentiated cells. The invention provides a bone filler for cartilage tissue regeneration comprising hydrogel having an interpenetrating network structure formed by two or more crosslinked network polymers or a semi-interpenetrating network structure formed by a crosslinked network polymer and a linear polymer. By filling the bone filler of the invention in a hole or a groove provided in subchondral bone just under damaged cartilage tissue, regeneration of the cartilage tissue or both the cartilage tissue and the subchondral bone can be promoted.
摘要翻译： 旨在提供一种医疗材料，其能够通过移植自体软骨组织，软骨替代或未分化细胞而不同于通过移植自体软骨组织的治疗方法，基于全新的概念实现软骨组织再生治疗的新方法。 本发明提供了一种用于软骨组织再生的骨填料，其包括具有由两个或更多个交联网状聚合物形成的互穿网络结构的水凝胶或由交联网状聚合物和线性聚合物形成的半互穿网络结构。 通过将本发明的骨填充物填充在刚好在受损的软骨组织下方的软骨下骨中的孔或槽中，可以促进软骨组织或软骨组织和软骨下骨两者的再生。
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公开(公告)号：US20100003328A1
公开(公告)日：2010-01-07
申请号：US12312829
申请日：2007-11-29
IPC分类号： A61K31/785 , A61K9/00 , A61K31/74 , A61K31/795 , A61P41/00
CPC分类号： A61L27/52 , A61L2430/02
摘要： It is intended to provide a medical material which enables a new method for cartilage tissue regeneration treatment based on an entirely new concept unlike a treatment method by transplantation of autologous cartilage tissue, a cartilage alternative or undifferentiated cells. The invention provides a bone filler for cartilage tissue regeneration comprising hydrogel having an interpenetrating network structure formed by two or more crosslinked network polymers or a semi-interpenetrating network structure formed by a crosslinked network polymer and a linear polymer. By filling the bone filler of the invention in a hole or a groove provided in subchondral bone just under damaged cartilage tissue, regeneration of the cartilage tissue or both the cartilage tissue and the subchondral bone can be promoted.
摘要翻译： 旨在提供一种医疗材料，其能够通过移植自体软骨组织，软骨替代或未分化细胞而不同于通过移植自体软骨组织的治疗方法，基于全新的概念实现软骨组织再生治疗的新方法。 本发明提供了一种用于软骨组织再生的骨填料，其包括具有由两个或更多个交联网状聚合物形成的互穿网络结构的水凝胶或由交联网状聚合物和线性聚合物形成的半互穿网络结构。 通过将本发明的骨填充物填充在刚好在受损的软骨组织下方的软骨下骨中的孔或槽中，可以促进软骨组织或软骨组织和软骨下骨两者的再生。
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