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公开(公告)号：US11795290B2
公开(公告)日：2023-10-24
申请号：US16631903
申请日：2018-07-19
CPC分类号： C08J9/36 , A61F5/0003 , A61K9/0065 , A61K9/284 , A61K9/286 , A61K9/4816 , C08J3/075 , C08J3/246 , C08J9/0028 , C08J9/0061 , C08G2210/00 , C08G2230/00 , C08J2205/022 , C08J2207/10 , C08J2305/04 , C08J2305/08 , C08J2339/06 , C08J2371/02 , C08J2405/08 , C08J2439/06
摘要： The invention relates to novel a high-volume swelling hydrogel which comprises a plurality of pores which are defined by an interpenetrating network, and/or a semi-interpenetrating network and/or simple cross-linked arrangement of a plurality of one or more species of hydrophilic polymers, optionally together with one or more biocompatible polymers and optionally together with one or more plasticising agents, characterised in that at least some of the pores are at least partially collapsed and/or flattened, and further characterised in that the interpenetrating network and/or semi-interpenetrating network and/or cross-linked arrangement which defines the collapsed and/or flattened pores is substantially unbroken. The invention also relates to a process for preparing such hydrogels, and to their use as an appetite suppressant.
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公开(公告)号：US20240092977A1
公开(公告)日：2024-03-21
申请号：US17768057
申请日：2020-10-12
CPC分类号： C08J3/075 , A61K9/0056 , A61K47/34 , C08J3/246
摘要： The invention provides a process for preparing a plasticised superporous hydrogel material comprising subjecting initial hydrogel material to treatment with an acidic solution, an optional treatment with a monovalent metal salt solution, freeze drying and plasticisation. Optionally, the process of the invention produces moulded plasticised superporous hydrogel material bodies that have one or more through-holes formed therein. The plasticised superporous hydrogel material of the present invention may be formulated as a suitable oral dosage form for use an appetite suppressant and for use to deliver a pharmaceutical and/or nutraceutical into a human or animal body.
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公开(公告)号：US20230416489A1
公开(公告)日：2023-12-28
申请号：US18367636
申请日：2023-09-13
CPC分类号： C08J9/36 , C08J2439/06 , A61K9/0065 , A61K9/284 , A61K9/286 , A61K9/4816 , C08J9/0028 , C08J9/0061 , C08J3/075 , C08J3/246 , C08G2210/00 , C08G2230/00 , C08J2205/022 , C08J2207/10 , C08J2305/04 , C08J2305/08 , C08J2339/06 , C08J2371/02 , C08J2405/08 , A61F5/0003
摘要： The invention relates to novel a high-volume swelling hydrogel which comprises a plurality of pores which are defined by an interpenetrating network, and/or a semi-interpenetrating network and/or simple cross-linked arrangement of a plurality of one or more species of hydrophilic polymers, optionally together with one or more biocompatible polymers and optionally together with one or more plasticising agents, characterised in that at least some of the pores are at least partially collapsed and/or flattened, and further characterised in that the interpenetrating network and/or semi-interpenetrating network and/or cross-linked arrangement which defines the collapsed and/or flattened pores is substantially unbroken. The invention also relates to a process for preparing such hydrogels, and to their use as an appetite suppressant.
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公开(公告)号：US20200165406A1
公开(公告)日：2020-05-28
申请号：US16631903
申请日：2018-07-19
IPC分类号： C08J9/36 , A61K9/28 , A61K9/48 , A61L27/20 , A61K9/00 , C08J9/00 , A61F5/00 , A61L27/26 , A61L27/16
摘要： The invention relates to novel a high-volume swelling hydrogel which comprises a plurality of pores which are defined by an interpenetrating network, and/or a semi-interpenetrating network and/or simple cross-linked arrangement of a plurality of one or more species of hydrophilic polymers, optionally together with one or more biocompatible polymers and optionally together with one or more plasticising agents, characterised in that at least some of the pores are at least partially collapsed and/or flattened, and further characterised in that the interpenetrating network and/or semi-interpenetrating network and/or cross-linked arrangement which defines the collapsed and/or flattened pores is substantially unbroken. The invention also relates to a process for preparing such hydrogels, and to their use as an appetite suppressant.
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