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1440 条记录 (耗时 0.034 秒)

    Method for producing silicone hydrogel contact lenses
    4.
    发明授权
    Method for producing silicone hydrogel contact lenses 有权

    公开(公告)号：US12116442B2

    公开(公告)日：2024-10-15

    申请号：US17313459

    申请日：2021-05-06

    申请人： Alcon Inc.

    发明人： Jing Cheng ,  Yang Zheng ,  Steve Yun Zhang ,  Lindsay Olson

    IPC分类号： C08F283/12 ,  C08J3/075

    CPC分类号： C08F283/12 ,  C08J3/075 ,  C08J2383/10

    摘要： The invention provides a contact lens manufacturing method comprising a process for removing unprocessed molded silicone hydrogel contact lenses from mold halves in a relatively efficient and consistent manner. The method of the invention involves using a silicone fluid (or so-called silicone oil) as non-reactive diluent in SiHy lens formulation for making SiHy contact lenses. Resultant SiHy contact lenses cast-molded from such a SiHy lens formulation can have a significantly reduced adhesion force with the molding surfaces of a lens mold and consequently a higher efficiency and consistency in removing unprocessed molded SiHy contact lenses from mold halves can be achieved. This method of the invention can be easily implemented in a production environment for enhancing the production yield.

    POLYURETHANE-BASED RADIOPAQUE CROSSLINKED HYDROGELS WITH NON-ISOCYANATE PRECURSOR FOR MEDICAL APPLICATIONS
    7.
    发明公开
    POLYURETHANE-BASED RADIOPAQUE CROSSLINKED HYDROGELS WITH NON-ISOCYANATE PRECURSOR FOR MEDICAL APPLICATIONS 审中-公开

    公开(公告)号：US20240317944A1

    公开(公告)日：2024-09-26

    申请号：US18615619

    申请日：2024-03-25

    申请人： Boston Scientific Scimed, Inc.

    发明人： Yen-Hao Hsu

    IPC分类号： C08J3/075 ,  C08G18/10 ,  C08G18/30 ,  C08J3/24

    CPC分类号： C08J3/075 ,  C08G18/10 ,  C08G18/30 ,  C08J3/24 ,  C08J2375/04

    摘要： In some aspects, a system for forming a hydrogel composition is described that comprises (a) a multifunctional cyclic carbonate compound and (b) a radiopaque, reactive polymer that comprises a plurality of amino groups that are reactive with the multifunctional cyclic carbonate groups of the multifunctional cyclic carbonate compound. In other aspects, a radiopaque crosslinked hydrogel composition is described that comprises a crosslinked reaction product of a multifunctional cyclic carbonate compound and a radiopaque, reactive polymer that comprises a plurality of amino groups. In further aspects, a method of treatment is described that comprises administering to a subject a mixture that comprises a multifunctional cyclic carbonate compound and a radiopaque, reactive polymer that comprises a plurality of amino groups, wherein the mixture is administered under conditions such that the multifunctional cyclic carbonate compound and the radiopaque, reactive multi-arm polymer crosslink after administration.

    Bifunctional and flexible hydrogel optical fiber, preparation method and application thereof
    8.
    发明授权
    Bifunctional and flexible hydrogel optical fiber, preparation method and application thereof 有权

    公开(公告)号：US12099165B1

    公开(公告)日：2024-09-24

    申请号：US18656271

    申请日：2024-05-06

    申请人： Sichuan University

    发明人： Nan Jiang ,  Guoliang Ying ,  Hongze Li

    IPC分类号： G02B1/04 ,  C08J3/075

    CPC分类号： G02B1/046 ,  C08J3/075

    摘要： This application relates to a bifunctional and flexible hydrogel optical fiber, a preparation method and an application thereof. Raw materials of a fiber core include polyethylene glycol diacrylate (PEGDA), methacrylamide, 2-hydroxyethyl methacrylate (HEMA) and 2,2-diethoxy-phenylacetophenone (DMPA); raw materials of an intermediate fiber layer include Synechococcus cells, PEGDA, gelatin methacrylate (GelMA), anhydrous strontium chloride and DMPA; and raw materials of a cladding include PEGDA, methacrylamide, sodium alginate and DMPA. A continuous and controllable direct oxygen supply function is provided through an optical fiber structure.