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1.Piperazinone Derivatives Useful as Histamine H3 Receptor Antagonists and/or Inverse Agonists 审中-公开
标题翻译: 可用作组胺H3受体拮抗剂和/或反激动剂的哌嗪酮衍生物公开(公告)号:US20080275027A1
公开(公告)日:2008-11-06
申请号:US11995929
申请日:2006-07-17
申请人: Rachael Ann Ancliff , Mark James Bamford , Simon Teanby Hodgson , Christopher Allan Parr , Panayiotic Alexandrou Procopiou , David Matthew Wilson , Michael Woodrow
发明人: Rachael Ann Ancliff , Mark James Bamford , Simon Teanby Hodgson , Christopher Allan Parr , Panayiotic Alexandrou Procopiou , David Matthew Wilson , Michael Woodrow
IPC分类号: C07D241/08 , A61K31/497 , C07D401/12 , A61P37/00 , A61P37/08 , A61K31/55 , C07D403/12
CPC分类号: C07D487/04 , C07D241/18 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/06 , C07D409/14 , C07D413/10 , C07D417/14
摘要: The invention relates to compounds of formula (I) or salts and solvates thereof, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders, such as allergic rhinitis: wherein R1 and R2 are as defined in the specification.
摘要翻译: 本发明涉及式(I)化合物或其盐和溶剂合物,其制备方法,含有它们的组合物及其在治疗各种疾病如抗过敏性鼻炎中的用途:其中R 1〜 >和R 2-2如说明书中所定义。