公开(公告)号：US08951938B2

公开(公告)日：2015-02-10

申请号：US12340933

申请日：2008-12-22

申请人： Young-Tae Chang ,  Young-Hoon Ahn ,  Yun Kyung Kim ,  Bridget Wagner ,  Hyman A. Carrinski ,  Paul Clemons ,  Stuart Schreiber

发明人： Young-Tae Chang ,  Young-Hoon Ahn ,  Yun Kyung Kim ,  Bridget Wagner ,  Hyman A. Carrinski ,  Paul Clemons ,  Stuart Schreiber

IPC分类号： C40B30/04 ,  C40B30/06 ,  C12Q1/02 ,  G01N33/50

CPC分类号： G01N33/5073 ,  G01N33/5061 ,  Y10S436/80

摘要： The present invention relates to the use of rosamine derivative compounds, as described herein, in detecting differentiated forms of a cell type of interest in a sample and in screening for compounds which inhibit differentiation of the cell type of interest. The candidate compound has the following structure:

摘要翻译： 本发明涉及如本文所述的用于检测样品中感兴趣的细胞类型的分化形式以及筛选抑制感兴趣的细胞类型分化的化合物的用途。 候选化合物具有以下结构：

公开(公告)号：US20090227467A1

公开(公告)日：2009-09-10

申请号：US12340933

申请日：2008-12-22

申请人： Young-Tae CHANG ,  Young-Hoon AHN ,  Yun Kyung KIM ,  Bridget WAGNER ,  Hyman A. CARRINSKI ,  Paul CLEMONS ,  Stuart SCHREIBER

发明人： Young-Tae CHANG ,  Young-Hoon AHN ,  Yun Kyung KIM ,  Bridget WAGNER ,  Hyman A. CARRINSKI ,  Paul CLEMONS ,  Stuart SCHREIBER

IPC分类号： C40B30/04

CPC分类号： G01N33/5073 ,  G01N33/5061 ,  Y10S436/80

摘要： The present invention relates to the use of rosamine derivative compounds, as described herein, in detecting differentiated forms of a cell type of interest in a sample and in screening for compounds which inhibit differentiation of the cell type of interest. The candidate compound has the following structure:

摘要翻译： 本发明涉及如本文所述的用于检测样品中感兴趣的细胞类型的分化形式以及筛选抑制感兴趣的细胞类型分化的化合物的用途。 候选化合物具有以下结构：