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公开(公告)号:US07723028B2
公开(公告)日:2010-05-25
申请号:US10914396
申请日:2004-08-09
申请人: Kenneth Kornman , Paul Martha , Gordon W. Duff , Simon Van Dijk
发明人: Kenneth Kornman , Paul Martha , Gordon W. Duff , Simon Van Dijk
CPC分类号: C12Q1/6883 , C12Q2600/156 , C12Q2600/172
摘要: Diagnostics and therapeutics for osteoporosis, which are bases upon the identification of a subjects IL-1 haplotype and genotype pattern are described.
摘要翻译: 描述了基于鉴定受试者IL-1单倍型和基因型模式的骨质疏松症的诊断和治疗。
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2.
公开(公告)号:US20070015714A1
公开(公告)日:2007-01-18
申请号:US11343283
申请日:2006-01-30
申请人: Marc Garnick , Paul Martha , Christopher Molineaux , Alex DePaoli
发明人: Marc Garnick , Paul Martha , Christopher Molineaux , Alex DePaoli
IPC分类号: A61K38/09
摘要: Methods for treating FSH related conditions, such as prostatic intraepithelial neoplasia, pedophilia, infertility, or vaginal bleeding, with GnRH antagonists are disclosed. The methods of the invention generally feature administering to a subject a GnRH antagonist suitable for in vivo administration and able to reduce both plasma FSH and LH levels in a subject, in an amount or in a formulation effective to reduce plasma FSH levels in the subject to a symptom alleviating level. In vitro fertilization and male contraceptive methods are also provided.
摘要翻译: 公开了用GnRH拮抗剂治疗FSH相关病症如前列腺上皮内瘤变,恋童癖,不育症或阴道出血的方法。 本发明的方法通常特征在于向受试者施用适于体内施用的GnRH拮抗剂,并且能够降低受试者中的血浆FSH和LH水平,其量可以有效地降低受试者的血浆FSH水平, 症状缓解水平。 还提供体外受精和男性避孕方法。
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公开(公告)号:US20090023147A1
公开(公告)日:2009-01-22
申请号:US12142476
申请日:2008-06-19
申请人: Kenneth Kornman , Paul Martha , Gordon W. Duff , Simon Van Dijk , Nazneen Aziz , Hwa-Ying Wang
发明人: Kenneth Kornman , Paul Martha , Gordon W. Duff , Simon Van Dijk , Nazneen Aziz , Hwa-Ying Wang
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要: Diagnostics and therapeutics for osteoporosis, which are bases upon the identification of a subjects IL-1 haplotype and genotype pattern are described.
摘要翻译: 描述了基于鉴定受试者IL-1单倍型和基因型模式的骨质疏松症的诊断和治疗。
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公开(公告)号:US20050084882A1
公开(公告)日:2005-04-21
申请号:US10914396
申请日:2004-08-09
申请人: Kenneth Kormman , Paul Martha , Gordon Duff , Simon Dijk
发明人: Kenneth Kormman , Paul Martha , Gordon Duff , Simon Dijk
IPC分类号: A61B20060101 , C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/156 , C12Q2600/172
摘要: Diagnositics and therapeutics for osteoporosis, which are bases upon the identification of a subjects IL-1 haplotype and genotype patteren are described.
摘要翻译: 描述了基于鉴定受试者IL-1单倍型和基因型patteren的骨质疏松症的诊断和治疗。
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公开(公告)号:US20100255475A1
公开(公告)日:2010-10-07
申请号:US12687657
申请日:2010-01-14
申请人: Kenneth S. Kornman , Paul Martha , Gordon Duff , Simon Van Dijk , Nazneen Aziz , Hwa-Ying Wang , Venkateswarlu Kondragunta , Xiaodong Wu
发明人: Kenneth S. Kornman , Paul Martha , Gordon Duff , Simon Van Dijk , Nazneen Aziz , Hwa-Ying Wang , Venkateswarlu Kondragunta , Xiaodong Wu
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172
摘要: Diagnostics and therapeutics for osteoporosis, which are bases upon the identification of a subjects IL-1 haplotype and genotype pattern are described.
摘要翻译: 描述了基于鉴定受试者IL-1单倍型和基因型模式的骨质疏松症的诊断和治疗。
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