公开(公告)号：US20070173943A1

公开(公告)日：2007-07-26

申请号：US10543335

申请日：2004-01-16

Applicant: Gary Dulak ,  Anil Bhalani ,  Paul Molloy

Inventor： Gary Dulak ,  Anil Bhalani ,  Paul Molloy

IPC: A61F2/44

CPC classification number: A61F2/4611 ,  A61B17/00234 ,  A61F2/441 ,  A61F2/4601 ,  A61F2002/30088 ,  A61F2002/30583 ,  A61F2002/444 ,  A61F2002/4635 ,  A61F2210/008 ,  A61F2210/0085 ,  A61L27/26

Abstract: The present invention relates to an artificial nucleus pulposus implant that is injected minimally invasively into the nucleus cavity of the annulus fibrosus to restore the normal anatomical and physiological function of the spine in the affected disc segment. In one aspect of the invention, a device is disclosed for delivering a phase changing biomaterial to a tissue site, the device comprising a dispenser including (i) a plunger having a proximal portion and a distal portion, an inlet end and an outlet end, (ii) a dispensing actuator attached to the proximal portion of the plunger, and (iii) a cartridge adapted to be inserted into the inlet end of the plunger for containing the phase changing biomaterial in a fluid state. The dispenser may be mechanically, pneumatically or hydraulically actuated. The dispenser may further comprise a nozzle attached to the cartridge for dispensing the biomaterial to the tissue site. In another aspect, the device may further comprise a tissue cavity access unit providing a conduit having an inlet end in fluid communication with the nozzle, and an outlet end adapted to deliver the biomaterial to the tissue site. The biomaterial may transition from the fluid state to a solid state after a set amount of time, a temperature change or an exposure to an external stimuli such as radiation, UV light or an electrical stimuli. The cartridge may be a dual-chambered cartridge for storing different fluid biomaterials in the two chambers. In another aspect of the invention, a process for producing the artificial nucleus pulposus implant in the nucleus cavity of the annulus fibrosus is disclosed, the process comprising the steps of (a) obtaining access to the nucleus cavity; (b) injecting the artificial nucleus pulposus into the nucleus cavity; and (c) permitting the biomaterial to transition from a fluid state to a solid state in-situ after a given condition.

Abstract translation: 本发明涉及一种人造髓核植入物，其被最小程度地侵入到纤维环的细胞腔中，以恢复受影响椎间盘段脊柱的正常解剖和生理功能。 在本发明的一个方面，公开了一种用于将相变生物材料输送到组织部位的装置，该装置包括分配器，该分配器包括（i）具有近端部分和远端部分的柱塞，入口端和出口端， （ii）附接到柱塞的近端部分的分配致动器，以及（iii）适于插入到柱塞入口端的筒，用于容纳处于流体状态的相变生物材料。 分配器可以是机械的，气动的或液压致动的。 分配器还可以包括连接到盒的喷嘴，用于将生物材料分配到组织部位。 在另一方面，所述装置还可以包括组织腔进入单元，其提供具有与所述喷嘴流体连通的入口端的导管，以及适于将生物材料输送到组织部位的出口端。 生物材料可以在经过一定时间，温度变化或暴露于诸如辐射，紫外光或电刺激的外部刺激之后从流体状态转变为固态。 盒可以是用于在两个腔室中存储不同流体生物材料的双腔筒。 在本发明的另一方面，公开了一种在纤维环的细胞腔内制备人造髓核植入物的方法，该方法包括以下步骤：（a）获得进入核腔的步骤; （b）将人造髓核注入核腔; 和（c）允许生物材料在给定条件之后从原位流体状态转变为固态。

公开(公告)号：US06399930B2

公开(公告)日：2002-06-04

申请号：US09900228

申请日：2001-07-06

Applicant: William Day ,  David Harter ,  Paul Molloy

Inventor： William Day ,  David Harter ,  Paul Molloy

IPC: H05B680

CPC classification number: H05B6/6476

Abstract: A combination convection/microwave oven in which a food product is cooked by microwave energy and by a heated airflow provided by a thermal energy source and a blower. The oven is capable of cooking food in a microwave reflective pan. Microwave energy enters the oven below the pan and is guided to a spacing between the pan and oven sides and then reflected by the sides and top of the oven to the food product in the pan. The heated airflow is laminar with an upper layer and a lower layer. The pan is positioned at about the interface of the two layers so that the upper layer is incident on the food product and the lower layer is incident on the bottom of the pan.

公开(公告)号：US06595117B1

公开(公告)日：2003-07-22

申请号：US09632417

申请日：2000-08-04

Applicant: Douglas Jones ,  William Day ,  David Harter ,  Gerald W. Sank ,  Paul Molloy

Inventor： Douglas Jones ,  William Day ,  David Harter ,  Gerald W. Sank ,  Paul Molloy

IPC: A47J3708

CPC classification number: A21B1/245 ,  A47J37/0857

Abstract: A cooking appliance which is capable of rapidly toasting a food product disposed therein by air impingement and infrared heating to provide a cooked food product having the desired color and crunchiness about its surface. The appliance is particularly adapted for cooking sandwich products, toasting the bread and heating the sandwich filler. The appliance includes an air impingement assembly that delivers columns of heated air to the food product and an infrared heater assembly that produces infrared energy. The appliance delivers the impingement air from above the food product and the infrared energy from below. Alternatively, the appliance delivers the impingement air from above and below the food product and the infrared energy from below.

Abstract translation: 一种烹饪器具，其能够通过空气冲击和红外线加热来快速烘烤设置在其中的食品，以提供具有期望的颜色和在其表面上的脆性的烹饪食品。 该器具特别适用于烹饪三明治产品，烘烤面包并加热夹心填料。 该器具包括一个空气冲击组件，其将一列加热的空气输送到食品和一个产生红外能量的红外线加热器组件。 该设备从食物上方传送冲击空气，并从下方传递红外能量。 或者，该器具从食物的上方和下方输送冲击空气，并从下方输送红外线能量。