专利检索 ap:"Paula Pith-Rowe" 第 1 页

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发明申请
Methods and compositions for treating and preventing infection using human interferon regulatory factor 3 审中-公开
标题翻译：使用人类干扰素调节因子3治疗和预防感染的方法和组合物

公开(公告)号：US20050054033A9

公开(公告)日：2005-03-10

申请号：US09975253

申请日：2001-10-12

申请人： Paul Moore , Paula Pith-Rowe

发明人： Paul Moore , Paula Pith-Rowe

IPC分类号： A61K38/00 , C07K14/47 , C07K14/705 , C07H21/04 , C12N5/06 , C12P21/02

CPC分类号： C07K14/4702 , A61K38/00 , C07K14/47 , C12N2799/027

摘要： The present invention relates to IRF3 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human IRF3 protein. IRF3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods of gene therapy using polynucleotides encoding IRF3 polypeptides, fragments or variants to treat, prevent or ameliorate infectious diseases.

摘要翻译： 本发明涉及IRF3多肽。特别地，提供编码人IRF3蛋白的分离的核酸分子。还提供了IRF3多肽，载体，宿主细胞和用于制备它们的重组方法。本发明还涉及使用编码IRF3多肽，片段或变体的多核苷酸来治疗，预防或改善感染性疾病的基因治疗的筛选方法。