公开(公告)号：US07033348B2

公开(公告)日：2006-04-25

申请号：US10119914

申请日：2002-04-10

申请人： Robert R. Alfano ,  Jing Tang ,  Jonathan M. Evans ,  Peng Pei Ho

发明人： Robert R. Alfano ,  Jing Tang ,  Jonathan M. Evans ,  Peng Pei Ho

IPC分类号： A61B18/18

CPC分类号： A61B17/00491 ,  A61B17/0057 ,  A61B2017/00004 ,  A61B2017/00517 ,  A61B2017/00641 ,  A61B2017/0065

摘要： Laser tissue welding can be achieved using tunable Cr4+ lasers, semiconductor lasers and fiber lasers, where the weld strength follows the absorption spectrum of water. The use of gelatin and esterified gelatin as solders in conjunction with laser inducted tissue welding impart much stronger tensile and torque strengths than albumin solders. Selected NIR wavelength from the above lasers can improve welding and avoid thermal injury to tissue when used alone or with gelatin and esterified gelatin solders. These discoveries can be used to enhance laser tissue welding of tissues such as skin, mucous, bone, blood vessel, nerve, brain, liver, pancreas, spleen, kidney, lung, bronchus, respiratory track, urinary tract, gastrointestinal tract, or gynecologic tract and as a sealant for pulmonary air leaks and fistulas such as intestinal, rectal and urinary fistulas.

摘要翻译： 可以使用可调谐的Cr 4+激光器，半导体激光器和光纤激光器实现激光组织焊接，其中焊接强度遵循水的吸收光谱。 使用明胶和酯化明胶作为焊料与激光诱导组织焊接相结合赋予比白蛋白焊料更强的拉伸和扭矩强度。 来自上述激光器的选择的近红外波长可以改善焊接，并避免单独使用或与明胶和酯化明胶焊料一起使用时对组织的热损伤。 这些发现可用于增强组织如皮肤，粘液，骨骼，血管，神经，脑，肝脏，胰腺，脾脏，肾脏，肺，支气管，呼吸道，尿道，胃肠道或妇科组织的激光组织焊接 作为肺气体泄漏和瘘管如肠，直肠和尿瘘的密封剂。