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公开(公告)号：US08940339B2
公开(公告)日：2015-01-27
申请号：US13494554
申请日：2012-06-12
申请人： Per Wollmer , Morgan Andersson , Lennart Greiff , Thomas Landh
发明人： Per Wollmer , Morgan Andersson , Lennart Greiff , Thomas Landh
IPC分类号： A61K9/00 , A61K9/107 , A61K31/473 , A61K31/56 , A61K31/573 , A61K47/44
CPC分类号： A61K9/1075 , A61K9/0043 , A61K9/006 , A61K31/473 , A61K31/56 , A61K31/573 , A61K47/44
摘要： The invention relates to novel microemulsions comprising a non-polar lipid, at least one polar solvent, a surfactant, and a polar lipid. A microemulsion of these ingredients provides an environment that substantially encloses airborne particles, and it can be used for entrapping such particles. The inventive microemulsions are especially adapted for the prevention of symptoms in mammals, which are indirectly or directly caused by airborne particles. The invention further provides compositions comprising such microemulsions and methods of treatment comprising administering the same.
摘要翻译： 本发明涉及包含非极性脂质，至少一种极性溶剂，表面活性剂和极性脂质的新型微乳液。 这些成分的微乳液提供了基本上封闭空气传播颗粒的环境，并且其可以用于捕获这种颗粒。 本发明的微乳液特别适用于预防由空气传播的颗粒间接或直接引起的哺乳动物的症状。 本发明进一步提供了包含这种微乳液的组合物和治疗方法，其包括施用它们。
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公开(公告)号：US20060269578A1
公开(公告)日：2006-11-30
申请号：US10563828
申请日：2004-07-07
申请人： Per Wollmer , Morgan Andersson , Lennart Grief , Thomas Landh
发明人： Per Wollmer , Morgan Andersson , Lennart Grief , Thomas Landh
IPC分类号： A61K31/56 , A61K9/00 , A61K31/573 , A61K31/473
CPC分类号： A61K9/1075 , A61K9/0043 , A61K9/006 , A61K31/473 , A61K31/56 , A61K31/573 , A61K47/44
摘要： The invention relates to novel microemulsions comprising a non-polar lipid, at least one polar solvent, a surfactant, and a polar lipid. A microemulsion of these ingredients provides an environment that substantially encloses airborne particles, and it can be used for entrapping such particles. The inventive microemulsions are especially adapted for the prevention of symptoms in mammals, which are indirectly or directly caused by airborne particles. The invention further provides compositions comprising such microemulsions and methods of treatment comprising administering the same.
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公开(公告)号：US20130115305A1
公开(公告)日：2013-05-09
申请号：US13494554
申请日：2012-06-12
申请人： Per WOLLMER , Morgan Andersson , Lennart Greiff , Thomas Landh
发明人： Per WOLLMER , Morgan Andersson , Lennart Greiff , Thomas Landh
IPC分类号： A61K9/107
CPC分类号： A61K9/1075 , A61K9/0043 , A61K9/006 , A61K31/473 , A61K31/56 , A61K31/573 , A61K47/44
摘要： The invention relates to novel microemulsions comprising a non-polar lipid, at least one polar solvent, a surfactant, and a polar lipid. A microemulsion of these ingredients provides an environment that substantially encloses airborne particles, and it can be used for entrapping such particles. The inventive microemulsions are especially adapted for the prevention of symptoms in mammals, which are indirectly or directly caused by airborne particles. The invention further provides compositions comprising such microemulsions and methods of treatment comprising administering the same.
摘要翻译： 本发明涉及包含非极性脂质，至少一种极性溶剂，表面活性剂和极性脂质的新型微乳液。 这些成分的微乳液提供了基本上封闭空气传播颗粒的环境，并且其可以用于捕获这种颗粒。 本发明的微乳液特别适用于预防由空气传播的颗粒间接或直接引起的哺乳动物的症状。 本发明进一步提供了包含这种微乳液的组合物和治疗方法，其包括施用它们。
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公开(公告)号：US08211448B2
公开(公告)日：2012-07-03
申请号：US10563828
申请日：2004-07-07
申请人： Per Wollmer , Morgan Andersson , Lennart Greiff , Thomas Landh
发明人： Per Wollmer , Morgan Andersson , Lennart Greiff , Thomas Landh
CPC分类号： A61K9/1075 , A61K9/0043 , A61K9/006 , A61K31/473 , A61K31/56 , A61K31/573 , A61K47/44
摘要： The invention relates to novel microemulsions comprising a non-polar lipid, at least one polar solvent, a surfactant, and a polar lipid. A microemulsion of these ingredients provides an environment that substantially encloses airborne particles, and it can be used for entrapping such particles. The inventive microemulsions are especially adapted for the prevention of symptoms in mammals, which are indirectly or directly caused by airborne particles. The invention further provides compositions comprising such microemulsions and methods of treatment comprising administering the same.
摘要翻译： 本发明涉及包含非极性脂质，至少一种极性溶剂，表面活性剂和极性脂质的新型微乳液。 这些成分的微乳液提供了基本上封闭空气传播颗粒的环境，并且其可以用于捕获这种颗粒。 本发明的微乳液特别适用于预防由空气传播的颗粒间接或直接引起的哺乳动物的症状。 本发明进一步提供了包含这种微乳液的组合物和治疗方法，其包括施用它们。
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公开(公告)号：US06770619B2
公开(公告)日：2004-08-03
申请号：US09945242
申请日：2001-08-31
IPC分类号： C07K14785
CPC分类号： A61K9/0082 , Y10S514/826 , Y10S514/975
摘要： Lung surfactant compositions are provided which can form a swelling phase when dispersed in a medium containing electrolytes. Hereby, a more active spreading of the lung surfactant into the alveoli can be obtained after administration to the lungs. Further provided are a pharmaceutical composition and a pharmaceutical kit comprising a lung surfactant composition as well as to a method for the treatment, prevention and/or diagnosis of respiratory distress syndrome or other pulmonary diseases that are associated with a deficiency of a lung surfactant.
摘要翻译： 提供了肺表面活性剂组合物，其在分散在含有电解质的培养基中时可形成溶胀相。 因此，在给予肺后可以获得肺表面活性剂进入肺泡的更积极的扩散。 还提供了包含肺表面活性剂组合物的药物组合物和药物试剂盒，以及用于治疗，预防和/或诊断与肺表面活性剂缺乏相关的呼吸窘迫综合征或其它肺部疾病的方法。
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