Method and kit for separation of glycoproteins
    1.
    发明授权
    Method and kit for separation of glycoproteins 失效
    用于分离糖蛋白的方法和试剂盒

    公开(公告)号:US4269605A

    公开(公告)日:1981-05-26

    申请号:US52474

    申请日:1979-06-27

    摘要: Glycoproteins, especially glycosylated hemoglobins, are separated from non-glycosylated proteins, by complexing with a dihydroxyboryl reactive agent. The resulting complex can be separated physically from the non-glycosylated protein, making possible the determination of glycosylated hemoglobin content of lysed blood; a reactive agent and a kit are described for use in such determination and as a monitor in the control of diabetic treatment. The invention can also be used preparatively to isolate glycoproteins.

    摘要翻译: 通过与二羟基硼烷反应剂络合,糖蛋白,特别是糖基化血红蛋白与非糖基化蛋白质分离。 所得到的复合物可以与非糖基化蛋白物理分离,使得裂解血液中糖基化血红蛋白含量的测定成为可能; 描述了用于这种测定的反应剂和试剂盒以及用于控制糖尿病治疗的监测器。 本发明也可以制备性地用于分离糖蛋白。