公开(公告)号：US11645952B2

公开(公告)日：2023-05-09

申请号：US15269592

申请日：2016-09-19

申请人： Peter W. Cheung

发明人： Peter W. Cheung

IPC分类号： G06Q30/00 ,  G09F9/30 ,  G06Q30/0241 ,  G06Q30/0251 ,  G09F9/33 ,  G09F27/00 ,  G09F21/04

CPC分类号： G09F9/301 ,  G06Q30/0265 ,  G06Q30/0277 ,  G09F9/33 ,  G09F21/04 ,  G09F27/00 ,  G09F27/007

摘要： The present invention claims and disclose an improved portable, modular, segmental, universally mountable digit-roll display unit with modular, adjustable, expandable, customizable display, and, or members, which could be universally attached to a plurality of surfaces via a variety of combination of attachments. These functions allow for simple, organized, customizable portable digital signage solutions for the individual. All the individual user has to do is to attach or detach the universally mountable digit-roll display unit according to the display surface dimensions. This makes the apparatus ideal for a peer-to-peer, or a marketer-to-contractor network. In addition, it enables marketer to track geo-location and viewer metrics, in order to dynamically push suitable content to display units and to mobile devices of proximal viewers.

公开(公告)号：US5074977A

公开(公告)日：1991-12-24

申请号：US601940

申请日：1990-10-23

申请人： Peter W. Cheung ,  Edward B. Wieler ,  Clement E. Furlong, Jr.

发明人： Peter W. Cheung ,  Edward B. Wieler ,  Clement E. Furlong, Jr.

IPC分类号： G01N27/414

CPC分类号： G01N27/4148 ,  Y10S435/817 ,  Y10S436/806

摘要： A mearsuring instrument is disclosed having a reversibly selective binding protein immobilized upon the insulated-gate region of a field-effect transistor located on a sensor. With the sensor immersed in solution, the protein binds a select component of the solution to the gate producing an effect on a current flowing through the IGFET. A plurality of such binding protein-IGFET arrangements can be provided on the same sensor, including the same binding proteins having different binding coefficients K.sub.D or an array of proteins with different ligand specificity and/or affinity. Analysis of the IGFET's response to binding by a microprocessor allows, for example, the concentration of the component in solution to be determined. With a plurality of different binding proteins employed, the concentration of different components can be determined. Similarly, with binding proteins employed having different binding coefficients K.sub.D, the output of the sensor can be analyzed in either a digital or analog manner, or some combination of the two. To release the component from the protein, heat can be applied to the sensor through a resistive bank integrated into the sensor chip. Alternatively, the application of a reverse bias to the gate can be used to enhance release.

摘要翻译： 公开了一种测量仪器，其具有固定在位于传感器上的场效应晶体管的绝缘栅极区域上的可逆选择性结合蛋白。 当传感器浸入溶液中时，蛋白质将溶液的选择成分与栅极结合，产生对流过IGFET的电流的影响。 可以在同一传感器上提供多种这样的结合蛋白-IGIET配置，包括具有不同结合系数KD的相同结合蛋白或具有不同配体特异性和/或亲和力的蛋白质阵列。 IGFET对微结构的响应的分析允许例如溶液中组分的浓度被确定。 使用多种不同的结合蛋白，可以确定不同成分的浓度。 类似地，对于使用具有不同结合系数KD的结合蛋白，传感器的输出可以以数字或模拟方式或两者的某种组合进行分析。 为了从蛋白质释放组分，可以通过集成到传感器芯片中的电阻库将热量施加到传感器。 或者，可以使用向栅极施加反向偏压来增强释放。

公开(公告)号：US4892101A

公开(公告)日：1990-01-09

申请号：US315330

申请日：1989-02-24

申请人： Peter W. Cheung ,  Karl F. Gauglitz ,  Lee R. Mason ,  Stephen J. Prosser ,  Robert E. Smith ,  Darrell O. Wagner ,  Scott W. Hunsaker

发明人： Peter W. Cheung ,  Karl F. Gauglitz ,  Lee R. Mason ,  Stephen J. Prosser ,  Robert E. Smith ,  Darrell O. Wagner ,  Scott W. Hunsaker

IPC分类号： A61B5/00

CPC分类号： A61B5/14551

摘要： A feedback control system is disclosed for use in processing signals employed in pulse transmittance oximetry. The signals are produced in response to light transmitted through, for example, a finger at two different wavelengths. Each signal includes a slowly varying baseline component representing the relatively fixed attenuation of light produced by bone, tissue, skin, and hair. The signals also include pulsatile components representing the attenuation produced by the changing blood volume and oxygen saturation within the finger. The signals are processed by the feedback control system before being converted by an analog-to-digital (A/D) converter (72) for subsequent analysis by a microcomputer (16). The feedback control system includes a controllable offset subtractor (66), a programmable gain amplifier (68), controllable drivers (44) for the light sources (40, 42), and the microcomputer (16). The microcomputer (16) receives signals from the offset subtractor (66), gain amplifier (68), drivers (44) and A/D converter (72) to produce signals that control the function of the subtractor (66) and drivers (44) in the following manner. Normally, the drivers ( 44) are maintained within a predetermined current range. In the event the microcomputer (16) senses an output from the converter (72) that is not within a predetermined range, the drive signal is adjusted to produce an acceptable signal. The magnitude of the offset removed by the subtractor (66), as controlled by the microcomputer (16), is maintained at a constant level when the converter (72) output is within a first predetermined range and is a predetermined function of the converter (72) output when that output falls within a second predetermined range.

摘要翻译： 公开了一种反馈控制系统，用于处理脉冲透射比率测定中使用的信号。 信号是响应于透过例如两个不同波长的手指的光产生的。 每个信号包括缓慢变化的基线分量，其表示由骨，组织，皮肤和头发产生的光的相对固定的衰减。 信号还包括表示由手指内的血液体积变化和氧饱和度产生的衰减的脉动成分。 这些信号由模拟数字（A / D）转换器（72）转换之前由反馈控制系统处理，用于微计算机（16）的后续分析。 反馈控制系统包括可控偏移减法器（66），可编程增益放大器（68），用于光源（40,42）的可控驱动器（44）和微计算机（16）。 微型计算机（16）从偏移减法器（66），增益放大器（68），驱动器（44）和A / D转换器（72）接收信号，以产生控制减法器（66）和驱动器（44）的功能的信号 ）。 通常，驱动器（44）保持在预定的电流范围内。 在微计算机（16）感测到转换器（72）的输出不在预定范围内的情况下，调节驱动信号以产生可接受的信号。 当转换器（72）输出在第一预定范围内并且是转换器的预定功能时，被微计算机（16）控制的减法器（66）去除的偏移量的幅度保持在恒定水平 72）当该输出处于第二预定范围内时输出。

公开(公告)号：US5259381A

公开(公告)日：1993-11-09

申请号：US377722

申请日：1989-07-10

申请人： Peter W. Cheung ,  Karl F. Gauglitz ,  Scott W. Hunsaker ,  Stephen J. Prosser ,  Darrell O. Wagner ,  Robert E. Smith

发明人： Peter W. Cheung ,  Karl F. Gauglitz ,  Scott W. Hunsaker ,  Stephen J. Prosser ,  Darrell O. Wagner ,  Robert E. Smith

IPC分类号： A61B5/00 ,  A61B5/024 ,  G01N21/27

CPC分类号： G01N21/274 ,  A61B5/02427 ,  A61B5/14552 ,  A61B5/1495 ,  A61B2560/0252 ,  A61B2562/08

摘要： Under the present invention, a method and apparatus are provided for compensating for the effect temperature variations have on the wavelength of light emitted by the oximeter sensor light source (40, 42). In pulse oximetry, LEDs (40, 42) are typically employed to expose tissue to light at two different wavelengths. The light illuminating the tissue is received by a detector (38) where signals proportional to the intensity of light are produced. These signals are then processed by the oximeter circuitry to produce an indication of oxygen saturation. Because current oximetry techniques are dependent upon the wavelengths of light emitted by the LEDs (40, 42), the wavelengths must be known. Even when predetermined combinations of LEDs (40, 42) having relatively precise wavelengths are employed, variations in the wavelength of light emitted may result. Because the sensor (12) may be exposed to a significant range of temperatures while in use, the effect of temperature on the wavelengths may be significant. To compensate for this effect, a temperature sensor (50) is included in the sensor (12) to produce a signal indicative of sensor temperature. This signal is interpreted by the oximeter circuitry including, for example, a microcomputer (16), where the effect of temperature on wavelength is compensated for. In a preferred arrangement, this compensation takes the form of a computation of an alternative calibration curve from which the oxygen saturation is indicated, given a particular processing of signals from the detector (38).

摘要翻译： 在本发明中，提供了一种方法和装置，用于补偿由血氧计传感器光源（40,42）发射的光的波长对温度变化的影响。 在脉搏血氧测定中，通常使用LED（40,42）来将组织暴露于两个不同波长的光。 照射组织的光被检测器（38）接收，其中产生与光强度成比例的信号。 然后，这些信号由血氧计电路处理以产生氧饱和度的指示。 因为目前的血氧测定技术取决于由LED（40,42）发射的光的波长，所以波长必须是已知的。 即使当使用具有相对精确波长的LED（40,42）的预定组合时，也可能导致发射的光的波长的变化。 因为传感器（12）可能在使用时暴露于显着的温度范围内，所以温度对波长的影响可能是显着的。 为了补偿这种效果，传感器（12）中包括温度传感器（50），以产生指示传感器温度的信号。 该信号由包括例如温度对波长的影响得到补偿的微计算机（16）的血氧计电路解释。 在优选的布置中，给定来自检测器（38）的信号的特定处理，该补偿采用计算替代校准曲线的形式，从该氧化饱和度被指示。

公开(公告)号：USD317501S

公开(公告)日：1991-06-11

申请号：US107511

申请日：1987-10-09

申请人： Peter W. Cheung ,  Gary J. Selke

设计人： Peter W. Cheung ,  Gary J. Selke

公开(公告)号：US20180082615A1

公开(公告)日：2018-03-22

申请号：US15269592

申请日：2016-09-19

申请人： Peter W. Cheung

发明人： Peter W. Cheung

IPC分类号： G09F9/30 ,  G09G3/32 ,  G06Q30/02 ,  G09F9/33

CPC分类号： G09F9/301 ,  G06Q30/0265 ,  G06Q30/0277 ,  G09F9/33 ,  G09F21/04 ,  G09F27/00 ,  G09F27/007

摘要： The present invention claims and disclose an improved portable, modular, segmental, universally mountable digit-roll display unit with modular, adjustable, expandable, customizable display, and, or members, which could be universally attached to a plurality of surfaces via a variety of combination of attachments. These functions allow for simple, organized, customizable portable digital signage solutions for the individual. All the individual user has to do is to attach or detach the universally mountable digit-roll display unit according to the display surface dimensions. This makes the apparatus ideal for a peer-to-peer, or a marketer-to-contractor network. In addition, it enables marketer to track geo-location and viewer metrics, in order to dynamically push suitable content to display units and to mobile devices of proximal viewers.

公开(公告)号：US4913150A

公开(公告)日：1990-04-03

申请号：US897663

申请日：1986-08-18

申请人： Peter W. Cheung ,  Karl F. Gauglitz ,  Scott W. Hunsaker ,  Stephen J. Prosser ,  Darrell O. Wagner ,  Robert E. Smith

发明人： Peter W. Cheung ,  Karl F. Gauglitz ,  Scott W. Hunsaker ,  Stephen J. Prosser ,  Darrell O. Wagner ,  Robert E. Smith

IPC分类号： G01N21/31 ,  A61B5/00 ,  A61B5/024 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/27

CPC分类号： A61B5/02427 ,  A61B5/14552 ,  A61B5/1495 ,  G01N21/274 ,  A61B2560/0252 ,  A61B2562/08

摘要： Under the present invention, a method and apparatus are provided for compensating for the effect temperature variations have on the wavelength of light emitted by the oximeter sensor light sources (40, 42). In pulse oximetry, LEDs are typically employed to expose tissue to light at two different wavelengths. The light illuminating the tissue is received by a detector (38) where signals proportional to the intensity of light are produced. These signals are then processed by the oximeter circuitry to produce an indication of oxygen saturation. Because current oximetry techniques are dependent upon the wavelengths of light emitted by the LEDs (40-42), the wavelengths must be known. Even when predetermined combinations of LEDs (40-42) having relatively precise wavelengths are employed, variations in the wavelength of light emitted may result. Because the sensor (12) may be exposed to a significant range of temperatures while in use, the effect of temperature on the wavelengths may be significant. To compensate for this effect, a temperature sensor (50) is included in the sensor (12) to produce a signal indicative of sensor temperature. This signal is interpreted by the oximeter circuitry including, for example, a microcomputer (16), where the effect of temperature on wavelength is compensated for. In a preferred arrangement, this compensation takes the form of a computation of an alternative calibration curve from which the oxygen saturation is indicated, given a particular processing of signals from the detector (38).

公开(公告)号：US4819646A

公开(公告)日：1989-04-11

申请号：US897664

申请日：1986-08-18

申请人： Peter W. Cheung ,  Karl F. Gauglitz ,  Lee R. Mason ,  Stephen J. Prosser ,  Robert E. Smith ,  Darrell O. Wagner ,  Scott W. Hunsaker

发明人： Peter W. Cheung ,  Karl F. Gauglitz ,  Lee R. Mason ,  Stephen J. Prosser ,  Robert E. Smith ,  Darrell O. Wagner ,  Scott W. Hunsaker

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  A61B6/00

CPC分类号： A61B5/14551

摘要： A feedback control system is disclosed for use in processing signals employed in pulse transmittance oximetry. The signals are produced in response to light transmitted through, for example, a finger at two different wavelengths. Each signal includes a slowly varying baseline component representing the relatively fixed attenuation of light produced by bone, tissue, skin, and hair. The signals also include pulsatile components representing the attenuation produced by the changing blood volume and oxygen saturation within the finger. The signals are processed by the feedback control system before being converted by an analog-to-digital (A/D) converter (72) for subsequent analysis by a microcomputer (16). The feedback control system includes a controllable offset subtractor (66), a programmable gain amplifier (68), controllable drivers (44) for the light sources (40,42), and the microcomputer (16). The microcomputer receives signals from the offset subtractor (66), gain amplifier (68), drivers (44) and A/D converter (72) to produce signals that control the function of the subtractor (66) and drivers (44) in the following manner. Normally, the drivers (44) are maintained within a predetermined current range. In the event the microcomputer (16) senses an output from the converter (72) that is not within a predetermined range, the drive signal is adjusted to produce an acceptable signal. The magnitude of the offset removed by the subtractor (66), as controlled by the microcomputer (16), is maintained at a constant level when the converter (72) output is within a first predetermined range and is a predetermined function of the converter (72) output when that output falls within a second predetermined range.