公开(公告)号：US09968901B2

公开(公告)日：2018-05-15

申请号：US14549411

申请日：2013-05-21

Applicant: Steven Robert Head ,  Phillip T. Ordoukhanian ,  Daniel R. Salomon

Inventor： Steven Robert Head ,  Phillip T. Ordoukhanian ,  Daniel R. Salomon

IPC: C12Q1/68 ,  C40B40/06 ,  B01J19/00

CPC classification number: B01J19/0046 ,  B01J2219/0059 ,  B01J2219/00709 ,  B01J2219/00722 ,  C12Q1/6874 ,  C40B40/06 ,  C12Q2525/161 ,  C12Q2525/191 ,  C12Q2531/125 ,  C12Q2535/122 ,  C12Q2563/143

Abstract: The present disclosure provides methods, compositions, and kits for methods that can improve techniques nucleic acid analysis, and can allow for more reliable and accurate targeted, multiplexed, high throughput sequencing. The methods, compositions, and kits can be used for sequencing target loci of nucleic acid. The methods, compositions, and kits disclosed herein can be used for assisted de novo targeted sequencing. The methods, compositions, and kits disclosed herein can also be used for library labeling for de novo sequencing and phasing.

公开(公告)号：US20150265995A1

公开(公告)日：2015-09-24

申请号：US14549411

申请日：2013-05-21

Applicant: Steven Robert Head ,  Phillip T. Ordoukhanian ,  Daniel R. Salomon

Inventor： Steven Robert Head ,  Phillip T. Ordoukhanian ,  Daniel R. Salomon

IPC: B01J19/00 ,  C12Q1/68

CPC classification number: B01J19/0046 ,  B01J2219/0059 ,  B01J2219/00709 ,  B01J2219/00722 ,  C12Q1/6874 ,  C40B40/06 ,  C12Q2525/161 ,  C12Q2525/191 ,  C12Q2531/125 ,  C12Q2535/122 ,  C12Q2563/143

Abstract: The present disclosure provides methods, compositions, and kits for methods that can improve techniques nucleic acid analysis, and can allow for more reliable and accurate targeted, multiplexed, high throughput sequencing. The methods, compositions, and kits can be used for sequencing target loci of nucleic acid. The methods, compositions, and kits disclosed herein can be used for assisted de novo targeted sequencing. The methods, compositions, and kits disclosed herein can also be used for library labeling for de novo sequencing and phasing.

Abstract translation: 本公开提供了用于可以改进技术核酸分析的方法的方法，组合物和试剂盒，并且可以允许更可靠和准确的靶向多重的高通量测序。 方法，组合物和试剂盒可用于测序核酸靶基因座。 本文公开的方法，组合物和试剂盒可用于辅助的从头靶向测序。 本文公开的方法，组合物和试剂盒也可用于从头测序和定相的文库标记。