公开(公告)号：US09849193B2

公开(公告)日：2017-12-26

申请号：US14766726

申请日：2014-02-07

申请人： University of Louisville Research Foundation, Inc. ,  Ralph J. Knipp ,  Michael H. Nantz

发明人： Ralph J. Knipp ,  Michael H. Nantz

IPC分类号： A61K47/48 ,  A61K9/14 ,  A61K41/00

CPC分类号： A61K47/6923 ,  A61K41/0028 ,  A61K47/52 ,  A61K47/54 ,  A61K47/55 ,  A61K47/64 ,  A61K47/6929

摘要： The invention provides nanoparticles, methods for making nanoparticles, and methods for using nanoparticles. An important attribute of a drug delivery system is its ability to allow for spatial and temporal regulated drug release, thereby minimizing side effects and improving therapeutic efficacy of conventional pharmaceuticals. Iron oxide nanoparticles (NPs), specifically Fe304 nanoparticles, possess many appropriate qualities that make them a viable choice for drug delivery.

公开(公告)号：US20150374849A1

公开(公告)日：2015-12-31

申请号：US14766726

申请日：2014-02-07

申请人： Ralph J. KNIPP ,  Michael H. NANTZ ,  UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

发明人： Ralph J. KNIPP ,  Michael H. NANTZ

IPC分类号： A61K47/48

CPC分类号： A61K47/6923 ,  A61K41/0028 ,  A61K47/52 ,  A61K47/54 ,  A61K47/55 ,  A61K47/64 ,  A61K47/6929

摘要： The invention provides nanoparticles, methods for making nanoparticles, and methods for using nanoparticles. An important attribute of a drug delivery system is its ability to allow for spatial and temporal regulated drug release, thereby minimizing side effects and improving therapeutic efficacy of conventional pharmaceuticals. Iron oxide nanoparticles (NPs), specifically Fe304 nanoparticles, possess many appropriate qualities that make them a viable choice for drug delivery.

摘要翻译： 本发明提供纳米颗粒，制备纳米颗粒的方法和使用纳米颗粒的方法。 药物递送系统的一个重要特征是其能够允许空间和时间调节的药物释放，从而最小化副作用并改善常规药物的治疗功效。 氧化铁纳米粒子（NPs），特别是Fe304纳米粒子，具有许多合适的品质，使其成为药物递送的可行选择。