摘要:
Gene expression elements and their use in production of chimeric antibodies with human constant regions and murine variable regions, and mouse human chimeric antibodies having specificity to human tumor cells, methods of their production, and their use.
摘要:
A fluid dispensing tool includes parallel spaced first and second manifolds supporting therebetween an elongated actuator unit having a tubular body confining a piston connected to move a valve actuator stem projecting into a releasable coupler mounted on the second manifold. The manifolds also support therebetween a plurality of elongated valve units each having a tubular valve body defining a valve chamber and a chamber receiving a piston connected to move an elongated valve member. Each valve body has a port for receiving a corresponding fluid supply line or an evacuation line. The first manifold has separate passages connecting air control lines to the piston chambers for moving the actuator stem and each valve member axially. The second manifold has a fluid passage connecting each valve chamber to the coupler, and a handle supports the tool and a finger actuator connected to the coupler.
摘要:
A fluid dispensing tool assembly includes an upper tool unit having an evacuation port and a fluid inlet port with fluid actuated poppet valves selectively controlling the flow through each port to a center passage within the upper tool unit. The assembly also has a lower tool unit connected to the upper tool unit by a quick-release coupler and includes a center tube member projecting into the passage and also into the inlet portion of a fluid receiving system. The tube member is shifted axially by a fluid actuated piston within the lower tool unit to form a fluid-tight seal with the inlet portion after a second coupler secures the tool assembly to the inlet portion. A fluid-tight seal may be formed between an annular seat on a plastic inlet portion of the receiving system and an annular shoulder on the tube member within the lower tool unit.
摘要:
A chimeric antibody with human constant region and murine variable region, having specificity to a 35 kDA polypeptide (Bp35(CD20)) expressed on the surface of human B cells, methods of production, and uses.