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公开(公告)号:US20080208107A1
公开(公告)日:2008-08-28
申请号:US12017996
申请日:2008-01-22
申请人: Stuart McRae , Wendy E. Bowerman , Stephen W. Braun , Regina Spiehl , Bernadette Messier , David Farquhar
发明人: Stuart McRae , Wendy E. Bowerman , Stephen W. Braun , Regina Spiehl , Bernadette Messier , David Farquhar
CPC分类号: A61N1/327 , A61N1/0412 , A61N1/0428 , A61N1/0476 , A61N1/325
摘要: A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
摘要翻译: 一种用于将至少一种渗透性组合物输送到受试者的组织膜中的透皮渗透物递送系统,包括一次性基底,其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分,以及具有 背衬层和可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置,贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面,与衬底的引孔区间隔开对准。
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公开(公告)号:US08116860B2
公开(公告)日:2012-02-14
申请号:US12017996
申请日:2008-01-22
申请人: Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
发明人: Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
CPC分类号: A61N1/327 , A61N1/0412 , A61N1/0428 , A61N1/0476 , A61N1/325
摘要: A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
摘要翻译: 一种用于将至少一种渗透性组合物输送到受试者的组织膜中的透皮渗透物递送系统,包括一次性基底,其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分,以及具有 背衬层和可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置,贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面,与衬底的引孔区间隔开对准。
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公开(公告)号:US20120035555A1
公开(公告)日:2012-02-09
申请号:US13272592
申请日:2011-10-13
申请人: Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
发明人: Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
IPC分类号: A61M35/00
CPC分类号: A61N1/327 , A61N1/0412 , A61N1/0428 , A61N1/0476 , A61N1/325
摘要: A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
摘要翻译: 一种用于将至少一种渗透性组合物输送到受试者的组织膜中的透皮渗透物递送系统,包括一次性基底,其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分,以及具有 背衬层和可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置,贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面,与衬底的引孔区间隔开对准。
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公开(公告)号:US08641689B2
公开(公告)日:2014-02-04
申请号:US13272592
申请日:2011-10-13
申请人: Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
发明人: Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
CPC分类号: A61N1/327 , A61N1/0412 , A61N1/0428 , A61N1/0476 , A61N1/325
摘要: A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
摘要翻译: 一种用于将至少一种渗透性组合物输送到受试者的组织膜中的透皮渗透物递送系统,包括一次性基底,其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分,以及具有 背衬层和可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置,贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面,与衬底的引孔区间隔开对准。
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公开(公告)号:US5204429A
公开(公告)日:1993-04-20
申请号:US228543
申请日:1988-08-04
申请人: Walter Kaminsky , Regina Spiehl
发明人: Walter Kaminsky , Regina Spiehl
IPC分类号: C08F4/64 , C08F4/60 , C08F4/642 , C08F4/6592 , C08F32/04
CPC分类号: C08F32/04 , Y10S526/943
摘要: Crystalline, isotactic homopolymers of cycloolefins or elastic copolymers made from cycloolefins and linear olefins are obtained, without ring opening of the cycloolefins, at industrially favorable polymerization temperatures by means of a catalyst which comprises a stereorigid, chiral metallocene compound of groups IVb to VIb of the Periodic Table of the Elements and an aluminoxane.
摘要翻译: 通过催化剂,在工业上有利的聚合温度下,由环烯烃和直链烯烃制成的环状烯烃的全同立构均聚物或由环烯烃和直链烯烃制成的弹性共聚物得到,不用环烯烃开环,所述催化剂包含立体刚性的基团IVb至VIb的手性茂金属化合物 元素周期表和铝氧烷。
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