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1.发明申请METHODS AND COMPOSITION FOR TESTING, PREVENTING, AND TREATING ASPERGILLUS FUMIGATUS INFECTION 审中-公开测试，预防和治疗青蒿素感染的方法和组合公开(公告)号：US20140242085A1
公开(公告)日：2014-08-28
申请号：US14238143
申请日：2011-08-12
申请人： Yoshitsugu Miyazaki , Satoshi Yamagoe , Masunori Kajikawa , Masahito Sugiura , Reiko Itoh , Hirotaka Kumagai
发明人： Yoshitsugu Miyazaki , Satoshi Yamagoe , Masunori Kajikawa , Masahito Sugiura , Reiko Itoh , Hirotaka Kumagai
IPC分类号： C07K16/14 , G01N33/569
CPC分类号： C07K16/14 , A61K2039/505 , C07K14/38 , C07K2317/34 , G01N33/56961 , G01N2333/38
摘要： As a result of the analysis by an SST-REX method so as to identify a target molecule for treating and testing an Aspergillus fumigatus infection, a YMAF1 protein has been found out, which is mainly localized in the cell wall of Aspergillus fumigatus. Moreover, it has been found out that YMAF1 protein-deficient Aspergillus fumigatus has reduced spore-forming ability and pathogenicity. Further, it has been found out that the survival rate of experimental mice having aspergillosis (invasive Aspergillus model mice) is improved by preparing and administering an antibody against the YMAF1 protein. Furthermore, it has been found out that Aspergillus fumigatus can be detected with a favorable sensitivity by an ELISA system using the antibody.
摘要翻译： 作为通过SST-REX法分析以鉴定用于治疗和测试烟曲霉感染的靶分子的结果，已经发现YMAF1蛋白主要位于烟曲霉的细胞壁中。 此外，已经发现YMAF1蛋白缺乏的烟曲霉具有降低的孢子形成能力和致病性。 此外，已经发现，通过制备和施用针对YMAF1蛋白的抗体，改善了具有曲霉菌病（侵入性曲霉属模型小鼠）的实验小鼠的存活率。 此外，已经发现通过使用抗体的ELISA系统可以以良好的灵敏度检测烟曲霉。
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2.发明授权Information processing apparatus and method utilizing useful additional-information item 失效利用有用的附加信息项的信息处理装置和方法
公开(公告)号：US5819235A
公开(公告)日：1998-10-06
申请号：US12462
申请日：1993-02-02
申请人： Ryo Tamai , Hirofumi Endo , Mitsuaki Takeuchi , Reiko Itoh , Jun Ebata
发明人： Ryo Tamai , Hirofumi Endo , Mitsuaki Takeuchi , Reiko Itoh , Jun Ebata
CPC分类号： G06F17/30038 , G06F17/30017 , G06Q20/208
摘要： An attaching unit attaches an additional-information packet to a collection of main information, wherein the additional-information packet comprises sensory information corresponding to sensory impressions of a human being that has processed the collection of main information, the sensory impressions being with respect to circumstances under which the collection of main information has been processed.
摘要翻译： 附加单元将附加信息分组附加到主要信息的集合，其中附加信息分组包括对应于已经处理了主要信息的收集的人的感觉印象的感官信息，感觉印象是关于情况 主要信息的收集已被处理。
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3.发明授权Information processing apparatus and method utilizing useful additional information packet 失效利用有用的附加信息包的信息处理装置和方法
公开(公告)号：US6035282A
公开(公告)日：2000-03-07
申请号：US133515
申请日：1998-08-12
申请人： Ryo Tamai , Hirofumi Endo , Mitsuaki Takeuchi , Reiko Itoh , Jun Ebata
发明人： Ryo Tamai , Hirofumi Endo , Mitsuaki Takeuchi , Reiko Itoh , Jun Ebata
CPC分类号： G06F17/30038 , G06F17/30017 , G06Q20/208
摘要： An attaching unit attaches an additional-information packet to a collection of main information, wherein the additional-information packet comprises sensory information corresponding to sensory impressions of a human being that has processed the collection of main information, the sensory impressions being with respect to circumstances under which the collection of main information has been processed.
摘要翻译： 附加单元将附加信息分组附加到主要信息的集合，其中附加信息分组包括对应于已经处理了主要信息的收集的人的感觉印象的感官信息，感觉印象是关于情况 主要信息的收集已被处理。
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