公开(公告)号：US20100080987A1

公开(公告)日：2010-04-01

申请号：US12568494

申请日：2009-09-28

申请人： Richard Brendon Timmons ,  Dhiman Bhattacharyya ,  Kytai Troung Nguyen ,  Hao Xu

发明人： Richard Brendon Timmons ,  Dhiman Bhattacharyya ,  Kytai Troung Nguyen ,  Hao Xu

IPC分类号： C08F2/46 ,  B32B5/00

CPC分类号： C08F2/46 ,  C12N5/0068 ,  C12N2533/30 ,  Y10T428/265

摘要： The present invention provides a method for creating surface-tailored polymer coating for improved cells proliferation by converting one or more carbonaceous monomers each comprising one or more functional groups to a monomer vapor; contacting the monomer vapor and a substrate; and igniting a radio frequency plasma glow discharge to polymerize the monomer vapor to form surface-tailored polymer coating on the substrate at a thicknesses of between 25 and 300 nm and has a functional group surface density of between 3 and 9%, wherein the surface-tailored polymer coating enhances cell proliferation.

摘要翻译： 本发明提供了一种用于通过将一种或多种各自包含一个或多个官能团的含碳单体转化为单体蒸气来产生表面定制聚合物涂层以改善细胞增殖的方法; 使单体蒸气和基体接触; 并且点燃射频等离子体辉光放电以使单体蒸汽聚合以在基底上形成表面定制的聚合物涂层，其厚度为25至300nm，并且具有3至9％的官能团表面密度，其中， 定制的聚合物涂层增强细胞增殖。