Methods and apparatus for evaluating image focus
    1.
    发明授权
    Methods and apparatus for evaluating image focus 失效
    用于评估图像焦点的方法和装置

    公开(公告)号:US07469160B2

    公开(公告)日:2008-12-23

    申请号:US10419181

    申请日:2003-04-18

    IPC分类号: A61B6/00

    摘要: The invention provides methods of focusing an instrument for the acquisition of optical data from a tissue sample. Methods of the invention allow rapid focusing in the context of a diagnostic procedure in which rapid data acquisition is desirable. For example, inventive methods allow a user to focus an optical instrument quickly enough to obtain data within an optimal window of time following application of a chemical agent to the tissue. In one embodiment, a user focuses an optical instrument by aligning laser spots projected onto a tissue sample within rings that are superimposed at predetermined locations within the user's visual field. Preferred methods of the invention further comprise automatic validation to detect whether the spots are sufficiently well-aligned.

    摘要翻译: 本发明提供了一种聚焦仪器以从组织样本获取光学数据的方法。 本发明的方法允许在需要快速数据采集的诊断程序的上下文中进行快速聚焦。 例如,本发明的方法允许用户将光学仪器快速聚焦,以便在向组织施加化学试剂之后的最佳时间窗口内获得数据。 在一个实施例中,用户通过将投影在组织样本上的激光点对准在与用户的视野内的预定位置叠加的环内的环境中来聚焦光学仪器。 本发明的优选方法还包括自动验证以检测斑点是否足够良好地对齐。