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公开(公告)号：US3993667A
公开(公告)日：1976-11-23
申请号：US600996
申请日：1975-08-01
IPC分类号： C07D307/32
摘要： Ester and amide derivatives of three-hydroxycitric acid .gamma.-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.
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公开(公告)号：US3962275A
公开(公告)日：1976-06-08
申请号：US531494
申请日：1974-12-11
IPC分类号： C07J73/00 , C07D493/02
CPC分类号： C07J73/003
摘要： 7-Oxa steroids which may be substituted in the 3-position with a hydroxy or oxo group or in the 2-position with a hydroxymethylene group or in the 2- and 3-positions with a substituent that forms a 5-membered heterocyclic ring, useful as antigonadotropic agents and a method of preparing these 7-oxa steroids from 3-hydroxy .DELTA..sup.5 -steroids including intermediates in this process.
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公开(公告)号：US4113776A
公开(公告)日：1978-09-12
申请号：US844570
申请日：1977-10-25
IPC分类号： C07C279/18 , C07C335/16 , C07C335/32 , C07D295/13 , C07C133/10 , C07C129/12
CPC分类号： C07D295/13 , C07C279/18 , C07C335/16 , C07C335/32
摘要： Antihypertensively active thiourea derivatives of the formulas ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3 and X are as hereinafter described, as well as a method of using a compound of the formula ##STR2## wherein R.sub.1 ', R.sub.2 ', R.sub.3 and X are as previously described, or a compound of formula II as an anti-hypertensive agent, is described.
摘要翻译： 其中R，R 1，R 2，R 3和X如下文所述，其中R 1，R 2，R 3和X如下文所述，以及使用下式III的化合物的方法：其中R 1' ，R2'，R3和X如前所述，或作为抗高血压剂的式II化合物。
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公开(公告)号：US4028397A
公开(公告)日：1977-06-07
申请号：US600995
申请日：1975-08-01
IPC分类号： C07C103/167 , C07C103/37
CPC分类号： C07C235/14 , C07C2103/74
摘要： Ester and amide derivatives of threo-hydroxycitric acid .gamma.-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.
摘要翻译： 苏氨酸羟基柠檬酸γ-内酯的酯和酰胺衍生物抑制生物系统中的脂肪酸合成，并且可用于治疗肥胖症和纠正脂质异常的情况。
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公开(公告)号：US3992264A
公开(公告)日：1976-11-16
申请号：US598481
申请日：1975-07-23
IPC分类号： C07D313/00 , C12D9/00
CPC分类号： C07D313/00 , Y10S435/888
摘要： A new antibiotic, designated as antibiotic 1745A/X, is produced by the fermentation of the known microorganism Streptomyces antibioticus, ATCC 11891, using the novel compound erythronolide A oxime as the substrate. This new antibiotic is useful as an antibacterial agent.
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公开(公告)号：US4096276A
公开(公告)日：1978-06-20
申请号：US763172
申请日：1977-01-27
IPC分类号： A61K31/18 , A61K31/445 , A61P9/12 , C07C67/00 , C07C279/18 , C07C325/00 , C07C335/16 , C07C335/32 , C07D295/13 , A61K31/17
CPC分类号： C07D295/13 , C07C279/18 , C07C335/16 , C07C335/32
摘要： Antihypertensively active thiourea derivatives of the formulas ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3 and X are as hereinafter described,As well as a method of using a compound of the formula ##STR2## wherein R.sub.1 ', R.sub.2 ', R.sub.3 and X are as previously described,Or a compound of formula II as an anti-hypertensive agent, is described.
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公开(公告)号：US4007208A
公开(公告)日：1977-02-08
申请号：US601246
申请日：1975-08-01
IPC分类号： C07D307/32
摘要： Ester and amide derivatives of threo-hydroxycitric acid .gamma.-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.
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公开(公告)号：US3993668A
公开(公告)日：1976-11-23
申请号：US600997
申请日：1975-08-01
IPC分类号： C07D307/32
摘要： Ester and amide derivatives of three-hydroxycitric acid .gamma.-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.
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公开(公告)号：US4104285A
公开(公告)日：1978-08-01
申请号：US790164
申请日：1977-04-22
申请人： Hugo Gallo-Torres , Robert William Guthrie , James Guthrie Hamilton , Richard Wightman Kierstead , Ann Clare Sullivan
发明人： Hugo Gallo-Torres , Robert William Guthrie , James Guthrie Hamilton , Richard Wightman Kierstead , Ann Clare Sullivan
CPC分类号： C07J41/0066 , C07J3/005 , C07J41/0061 , C07J7/0005 , C07J9/00 , C07J9/005
摘要： Taurine and glycine derivatives of nor or bisnorcholanic acid or etiocholanic acid which are useful in increasing bile flow or decreasing lipid levels and their method of production from deoxycholic acid, including intermediates thereof.
摘要翻译： 可用于增加胆汁流动或降低脂质水平的去氧胆酸和二氢胆碱酸或者儿茶酚酸的牛磺酸和甘氨酸衍生物及其脱氧胆酸的生产方法，包括其中间体。
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公开(公告)号：US4006166A
公开(公告)日：1977-02-01
申请号：US601678
申请日：1975-08-01
IPC分类号： C07D307/32
摘要： Ester and amide derivatives of threo-hydroxycitric acid .gamma.-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.
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