公开(公告)号：US06783496B2

公开(公告)日：2004-08-31

申请号：US10286547

申请日：2002-11-01

申请人： Xiaohui Hao ,  Richard Yun Chiao

发明人： Xiaohui Hao ,  Richard Yun Chiao

IPC分类号： A61B814

CPC分类号： A61B8/481 ,  G01S7/52038 ,  G01S15/8952 ,  G01S15/8963

摘要： The contrast-to-tissue ratio is improved while imaging contrast infused tissue. A subject is infused with contrast medium having microbubbles at a fundamental frequency. First and second transmit pulses are transmitted into the subject. The first and second transmit pulses each comprise first, or basic, and second, or seed, signals. The basic signal has a frequency based on the fundamental frequency and the seed signal has a subharmonic frequency based on the frequency of the basic signal. The first and second transmit pulses are phase inverted with respect to each other. Received echoes from first and second transmit pulses are filtered at a subharmonic or ultraharmonic frequency to remove tissue response and pass microbubble response.

摘要翻译： 在对比度输注的组织成像的同时，改善了对比组织比。 用基本频率的微泡输注造影剂。 第一和第二发送脉冲被发送到被摄体。 第一和第二发射脉冲各自包括第一，或基本和第二或种子信号。 基本信号具有基于基频的频率，并且种子信号基于基本信号的频率具有次谐波频率。 第一和第二发送脉冲相对于彼此相位反相。 来自第一和第二发射脉冲的接收回波以次谐波或超谐波频率被滤波以去除组织响应并通过微泡响应。