公开(公告)号：US20240358353A1

公开(公告)日：2024-10-31

申请号：US18686158

申请日：2022-08-28

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Paul Sheeran ,  Liang Zhang ,  Thanasis Loupas

IPC分类号： A61B8/00 ,  A61B8/08 ,  G06F3/0482 ,  G06F3/04847

CPC分类号： A61B8/469 ,  A61B8/465 ,  A61B8/54 ,  G06F3/04847 ,  A61B8/481 ,  G06F3/0482

摘要： A display (150) for a contrast-enhanced examination ultrasound (CEUS) exam is disclosed. The display (150) includes a user interface (160) with an editable protocol (200) adapted to allow a user to select time-based actions and events of an upcoming CEUS exam on the display (150); a first time-bar display (300) adapted to allow the user to alter time-based actions during the CEUS exam, and to provide visual indications of upcoming actions on the display (150); and a second time-bar display (400) adapted to allow the user to display (150) images (512) and loops acquired during the CEUS exam on the display (150). A method (600) of controlling an imaging procedure is also described.

公开(公告)号：US12076590B2

公开(公告)日：2024-09-03

申请号：US17690523

申请日：2022-03-09

申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

发明人： Elisa E. Konofagou ,  Fabrice Marquet ,  Yao-Sheng Tung

IPC分类号： A61N7/00 ,  A61B8/08 ,  A61B17/00 ,  A61B17/22 ,  A61B17/225 ,  A61B90/00 ,  A61B90/10

CPC分类号： A61N7/00 ,  A61B8/0808 ,  A61B8/481 ,  A61B17/2258 ,  A61B2017/00106 ,  A61B2017/22008 ,  A61B2017/22089 ,  A61B90/10 ,  A61B2090/378 ,  A61B2503/40 ,  A61N2007/0039

摘要： Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions.

公开(公告)号：US20240277320A1

公开(公告)日：2024-08-22

申请号：US18429732

申请日：2024-02-01

申请人： FUJIFILM Healthcare Corporation

发明人： Yasuo Okuda

IPC分类号： A61B8/00 ,  A61B8/08 ,  G06T11/60 ,  G16H30/40

CPC分类号： A61B8/54 ,  A61B8/463 ,  A61B8/469 ,  A61B8/481 ,  G06T11/60 ,  G16H30/40 ,  G06T2210/41

摘要： An ultrasound diagnostic apparatus enables a user to easily select a target image from among a plurality of images captured by an image diagnostic apparatus. An identification unit identifies, as one image group, a plurality of images continuously captured at time intervals equal to or less than a predetermined time interval among a plurality of images captured by an image diagnostic apparatus. A display controller displays, on a display, the image group and an image other than the image group in a distinguishable manner. For example, the display controller displays the image group as one thumbnail image on the display, and displays the image other than the image group as one thumbnail image on the display.

公开(公告)号：US12048750B2

公开(公告)日：2024-07-30

申请号：US17888072

申请日：2022-08-15

申请人： Blaze Bioscience, Inc.

发明人： Stacey J. Hansen ,  Claudia Jochheim ,  Dennis M. Miller ,  Natalie Winblade Nairn ,  Julia E. Novak ,  Mark R. Stroud ,  Valorie R. Wiss ,  Kelly Byrnes-Blake ,  Scott Presnell

IPC分类号： A61K38/00 ,  A61B5/00 ,  A61B6/00 ,  A61B6/03 ,  A61B6/40 ,  A61K47/64 ,  A61K47/65 ,  A61K49/00 ,  A61K51/08 ,  A61P13/12 ,  A61P19/02 ,  C07K14/435 ,  C07K14/47 ,  C07K16/24 ,  A61B5/055 ,  A61B8/08

CPC分类号： A61K47/6415 ,  A61B5/0071 ,  A61B6/037 ,  A61B6/4057 ,  A61B6/481 ,  A61K47/65 ,  A61K49/0056 ,  A61K49/0058 ,  A61K51/08 ,  A61P13/12 ,  A61P19/02 ,  C07K14/43518 ,  C07K14/43522 ,  C07K14/4726 ,  C07K16/244 ,  C07K16/248 ,  A61B5/055 ,  A61B8/481 ,  A61B2505/05 ,  C07K2319/30 ,  C07K2319/33 ,  C07K2319/50

摘要： Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures, or cells targeted by the peptide.

公开(公告)号：US12048467B2

公开(公告)日：2024-07-30

申请号：US17357483

申请日：2021-06-24

申请人： May Health US Inc.

发明人： Denise Marie Zarins ,  Neil Chand Barman ,  Garrett Marc Schwab ,  Andrew Wu

IPC分类号： A61B18/12 ,  A61B8/08 ,  A61B8/12 ,  A61B10/00 ,  A61B17/02 ,  A61B17/14 ,  A61B17/34 ,  A61B17/42 ,  A61B18/00 ,  A61B18/02 ,  A61B18/14 ,  A61B18/22 ,  A61B90/00 ,  A61N7/02 ,  A61B17/00 ,  A61B17/32 ,  A61B17/425 ,  A61B18/18 ,  A61B34/20

CPC分类号： A61B18/00 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/481 ,  A61B10/0045 ,  A61B17/0218 ,  A61B17/142 ,  A61B17/3403 ,  A61B17/3468 ,  A61B17/42 ,  A61B18/02 ,  A61B18/1482 ,  A61B18/1485 ,  A61B18/22 ,  A61B90/37 ,  A61N7/022 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61B2017/00123 ,  A61B2017/00132 ,  A61B2017/00137 ,  A61B2017/00477 ,  A61B2017/00557 ,  A61B2017/00566 ,  A61B2017/00876 ,  A61B2017/320044 ,  A61B2017/3413 ,  A61B2017/3486 ,  A61B2017/3488 ,  A61B17/425 ,  A61B2018/00005 ,  A61B2018/00273 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00791 ,  A61B2018/0212 ,  A61B2018/1246 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1861 ,  A61B2034/2063 ,  A61B2090/378 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2217/005 ,  A61B2217/007 ,  A61N2007/025

摘要： Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may also be useful in the treatment of infertility associated with PCOS.

公开(公告)号：US20240206856A1

公开(公告)日：2024-06-27

申请号：US18596155

申请日：2024-03-05

申请人： Insightec Ltd.

发明人： Yoav Levy ,  Oleg Prus

IPC分类号： A61B8/08 ,  A61B5/055 ,  A61N7/00

CPC分类号： A61B8/5269 ,  A61B8/481 ,  A61B5/055 ,  A61N2007/0039 ,  A61N2007/0052 ,  A61N2007/0095

摘要： Various approaches for focusing an ultrasound transducer having multiple transducer elements include causing the transducer elements to transmit ultrasound waves to a first one or more target regions and measure reflections of the ultrasound waves off the first one or more target regions; and based at least in part on the measured reflections, determining a parameter value associated with at least one of the transducer elements so as to generate an ultrasound focus at a second target region, different from the first one or more target regions.

公开(公告)号：US12004907B1

公开(公告)日：2024-06-11

申请号：US17453908

申请日：2021-11-08

申请人： PFOmetrix, LLC

发明人： Philip E. Eggers ,  Andrew R. Eggers ,  David Thomas Dobson

IPC分类号： A61B8/08 ,  A61B5/00 ,  A61B5/02 ,  A61B5/026 ,  A61B5/087 ,  A61B8/00 ,  A61B8/06 ,  G06T7/00 ,  A61M25/10

CPC分类号： A61B8/481 ,  A61B5/02028 ,  A61B5/026 ,  A61B8/44 ,  A61B8/4416 ,  A61B8/4477 ,  A61B8/4494 ,  A61B8/46 ,  A61B8/461 ,  A61B8/467 ,  A61B8/488 ,  A61B8/52 ,  G06T7/0012 ,  A61B5/087 ,  A61B5/742 ,  A61B8/06 ,  A61M2025/102

摘要： A system for detecting/quantifying the conductance of a right-to-left cardiac shunt includes a mouthpiece assembly, a solenoid-driven vacuum/pressurization assembly; a controller for operating the solenoid-driven vacuum/pressurization assembly; and a monitor for displaying the instructions from the controller. A microbubble counting cell and digital image sensor are combined with software-based image analysis to determine a number of microbubbles contained in a microbubble counting zone. A monitor enables operator specification of total volume of contrast agent to be injected into the patient. One or more first Doppler ultrasound transducer arrays are positioned adjacent to targeted intracranial arteries at one side of the skull or a pair of first Doppler ultrasound transducer arrays positioned adjacent to targeted intracranial arteries at both sides of the skull. A second Doppler ultrasound transducer is positioned on the precordium of the patient to detect the arrival of microbubble-containing contrast agent in the right atrium of the patient.

公开(公告)号：US11980414B2

公开(公告)日：2024-05-14

申请号：US18061339

申请日：2022-12-02

申请人： MicroCube, LLC

发明人： Dinesh I. Mody ,  Ketan Shroff ,  Amrish J. Walke ,  Clarence Emmons ,  Grason Ott ,  Michael Dobrowski ,  Meera Mody

IPC分类号： A61B1/018 ,  A61B1/00 ,  A61B1/04 ,  A61B1/303 ,  A61B1/32 ,  A61B8/08 ,  A61B8/12 ,  A61B18/14 ,  A61B18/00

CPC分类号： A61B18/1492 ,  A61B1/00078 ,  A61B1/00135 ,  A61B1/303 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/481 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00982

摘要： The present invention discloses access devices and methods to create an access channel for introduction of one or more working devices into an anatomical region. The access channel is created using a visualization modality that is later removed before inserting one or more working devices through the access channel. This allows the methods and devices of the present invention to be used even in small sized natural or surgically created insertion tracts leading to the anatomical region. The access channel can be made of a device such as a sheath, a guidewire, and an elongate device comprising a lumen. Examples of visualization modalities are endoscopes and body insertable ultrasound imaging devices. The working devices can be used to perform a variety of diagnostic, therapeutic, or preventive procedures. Endometrial ablation devices and procedures have been used as an example to describe various aspects of the present invention.

公开(公告)号：US11883238B1

公开(公告)日：2024-01-30

申请号：US17453912

申请日：2021-11-08

申请人： PFOmetrix, LLC

发明人： Philip E. Eggers ,  Andrew R. Eggers ,  David Thomas Dobson

IPC分类号： A61B8/08 ,  A61B8/00 ,  A61B5/026 ,  G06T7/00 ,  A61B5/02 ,  A61B8/06 ,  A61B5/00 ,  A61M25/10 ,  A61B5/087

CPC分类号： A61B8/481 ,  A61B5/026 ,  A61B5/02028 ,  A61B8/44 ,  A61B8/4416 ,  A61B8/4477 ,  A61B8/4494 ,  A61B8/46 ,  A61B8/461 ,  A61B8/467 ,  A61B8/488 ,  A61B8/52 ,  G06T7/0012 ,  A61B5/087 ,  A61B5/742 ,  A61B8/06 ,  A61M2025/102

摘要： A system for detecting/quantifying the conductance of a right-to-left cardiac shunt includes a mouthpiece assembly, a solenoid-driven vacuum/pressurization assembly; a controller for operating the solenoid-driven vacuum/pressurization assembly; and a monitor for displaying the instructions from the controller. A microbubble counting cell and digital image sensor are combined with software-based image analysis to determine a number of microbubbles contained in a microbubble counting zone. A monitor enables operator specification of total volume of contrast agent to be injected into the patient. One or more first Doppler ultrasound transducer arrays are positioned adjacent to targeted intracranial arteries at one side of the skull or a pair of first Doppler ultrasound transducer arrays positioned adjacent to targeted intracranial arteries at both sides of the skull. A second Doppler ultrasound transducer is positioned on the precordium of the patient to detect the arrival of microbubble-containing contrast agent in the right atrium of the patient.

公开(公告)号：US20240020841A1

公开(公告)日：2024-01-18

申请号：US18351084

申请日：2023-07-12

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Arash Kheradvar ,  Gianni Pedrizzetti

IPC分类号： G06T7/00 ,  G06T7/246 ,  G06T5/50 ,  A61B8/08 ,  A61B8/06 ,  G16H30/40

CPC分类号： G06T7/0014 ,  G06T7/246 ,  G06T5/50 ,  A61B8/481 ,  A61B8/06 ,  A61B8/483 ,  A61B8/0883 ,  G16H30/40 ,  G06T2200/04 ,  G06T2207/20212 ,  G06T2207/30048 ,  G06T2207/30104 ,  G06T2207/10132

摘要： Systems and methods for producing velocity data associated with three-dimensional (3D) flow field images. In some embodiments, the method includes receiving data associated with a plurality of frames of a flow field relating to image data acquired by a medical imaging device, in which the data includes information corresponding to measurements of the flow field over time within a chamber; performing, for each of the plurality of frames, the following operations including: generating, for a respective frame, a data correction based on an interaction of the flow field with the chamber, applying the data correction to a velocity field corresponding to the respective frame, and imposing an incompressibility constraint for the flow field on one or more data points of the respective frame; and generating, subsequent to imposing the incompressibility constraint, a plurality of corrected velocity fields each of which corresponds to one of the plurality of frames.