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公开(公告)号:US09938246B2
公开(公告)日:2018-04-10
申请号:US15282312
申请日:2016-09-30
IPC分类号: C07D249/06 , C07D401/04 , C07D405/04 , C07D409/04
CPC分类号: C07D249/06 , C07D401/04 , C07D405/04 , C07D409/04
摘要: The present invention relates to disubstituted triazoles, their synthesis, and their use as anti-cancer compounds. In particular, compounds of Formula (I) are provided.
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2.POLYMERASE, ENDONUCLEASE, AND HELICASE INHIBITORS AND METHODS OF USING THEREOF 审中-公开
标题翻译: 聚合酶,内切酶和有丝分裂抑制剂及其使用方法公开(公告)号:US20160075689A1
公开(公告)日:2016-03-17
申请号:US14786331
申请日:2014-04-23
申请人: Narsimha Reddy PENTHALA , Peter CROOKS , Robert EOFF , Grace COGGINS , Leena MADDUKRI , Jessica H. HARTMAN , Dae Song JANG , Alexei BASNAKIAN , Suja AARATTUTHODIYIL , Kevin RANEY , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
发明人: Narsimha Reddy Penthala , Peter Crooks , Robert Eoff , Grace Coggins , Leena Maddukuri , Jessica H. Hartman , Dae Song Jang , Alexei Basnakian , Suja Aarattuthodiyil , Kevin Raney
IPC分类号: C07D403/06
CPC分类号: C07D403/06
摘要: Inhibitors of DNA damage polymerases, endonucleases, and helicases are provided. In particular, compounds comprising Formula (I) are described.
摘要翻译: 提供了DNA损伤聚合酶,内切核酸酶和解旋酶的抑制剂。 特别地,描述了包含式(I)的化合物。
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公开(公告)号:US20170015635A1
公开(公告)日:2017-01-19
申请号:US15282312
申请日:2016-09-30
IPC分类号: C07D249/06 , C07D405/04 , C07D409/04 , C07D401/04
CPC分类号: C07D249/06 , C07D401/04 , C07D405/04 , C07D409/04
摘要: The present invention relates to disubstituted triazoles, their synthesis, and their use as anti-cancer compounds. In particular, compounds of Formula (I) are provided.
摘要翻译: 本发明涉及二取代三唑,其合成及其作为抗癌化合物的用途。 特别地,提供式(I)的化合物。
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