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公开(公告)号：US20070293531A1
公开(公告)日：2007-12-20
申请号：US11573097
申请日：2005-08-05
Applicant: Jakob Busch-Petersen , Roderick Davis , Dramane Laine , Christopher Neipp , Michael Palovich
Inventor： Jakob Busch-Petersen , Roderick Davis , Dramane Laine , Christopher Neipp , Michael Palovich
IPC: A61K31/439 , C07D221/22
CPC classification number: C07D451/14
Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
Abstract translation: 毒蕈碱乙酰胆碱受体拮抗剂及其使用方法。
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2.发明申请Crystallized hnf4 gamma ligand binding domain polypeptide and screening methods employing same 审中-公开结晶的hnf4γ配体结合域多肽和使用其的筛选方法公开(公告)号：US20050131209A1
公开(公告)日：2005-06-16
申请号：US10470958
申请日：2002-01-31
Applicant: Roderick Davis , Robert Johnson , Aaren Miller , James Way , Shawn Williams , Timothy Willson , George Wisely , Ann Kontz
Inventor： Roderick Davis , Robert Johnson , Aaren Miller , James Way , Shawn Williams , Timothy Willson , George Wisely , Ann Kontz
CPC classification number: C07K14/4702 , C07K2299/00
Abstract: A solved three-dimensional crystal structure of an HNF4g ligand binding domain polypeptide is disclosed, along with a crystal form of the HNF4g ligand binding domain. Methods of designing modulators of the biological activity of HNF4g, and other HNF4 ligand binding domain polypeptides are also disclosed.
Abstract translation: 公开了HNF4g配体结合结构域多肽的解决的三维晶体结构以及HNF4g配体结合结构域的晶体形式。 还公开了设计HNF4g和其他HNF4配体结合域多肽的生物学活性调节剂的方法。
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公开(公告)号：US20070185090A1
公开(公告)日：2007-08-09
申请号：US10598887
申请日：2004-03-17
Applicant: Jakob Busch-Petersen , Anthony Cooper , Roderick Davis , Dramane Laine , Michael Palovich , Wei Fu
Inventor： Jakob Busch-Petersen , Anthony Cooper , Roderick Davis , Dramane Laine , Michael Palovich , Wei Fu
IPC: A61K31/55 , C07D223/16
CPC classification number: C07D409/12 , C07D223/16 , C07D401/12 , C07D401/14 , C07D403/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
Abstract: Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.
Abstract translation: 提供毒蕈碱性乙酰胆碱受体拮抗剂及其使用方法。
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