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公开(公告)号：US06794508B2
公开(公告)日：2004-09-21
申请号：US10415922
申请日：2003-05-05
IPC分类号： C07D22118
CPC分类号： C07J75/00
摘要： An improved process for preparing steriods, such as 3-oxo-4-azasteroids, is described. Compounds of this type are known to be useful in the preparation of compounds having 5a-reductase inhibitor activity. The process comprises the hydrogenation of the corresponding steroid alkene in the presence of ammonium acetate, ammonium formate, and/or ammonium propionate and an appropriate catalyst.
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公开(公告)号：US4250327A
公开(公告)日：1981-02-10
申请号：US516
申请日：1979-01-02
IPC分类号： A23L1/275 , C09B69/10 , C07C143/55 , C07C69/353 , C07C101/26
CPC分类号： C09B69/109 , A23L5/47
摘要： A group of water-soluble polymeric yellow colors and their preparation is disclosed. These colors comprise a plurality of units of a chromophore of the formula ##STR1## wherein M.sup.+ is a pharmaceutically acceptable monovalent cation attached directly to amine units present in a nonchromophoric polymer backbone. In a preferred embodiment of the invention the backbone is a homopolymer or copolymer of vinylamine. These colorants find special utility as nonabsorbable colorants for edibles, especially foods and beverages, where their yellow hue is an excellent color match for existing monomeric azo food colors such as tartrazine, and as components of acid-insoluble pigment lakes which are themselves suitable for use in edibles.
摘要翻译： 公开了一组水溶性聚合黄色及其制备方法。 这些颜色包括多个单位的式IMAGF的发色团，其中M +是直接连接在非着色聚合物主链中的胺单元上的药学上可接受的一价阳离子。 在本发明的优选实施方案中，主链是乙烯基胺的均聚物或共聚物。 这些着色剂特别适用于食品，特别是食品和饮料的非吸收性着色剂，其中黄色色调与现有的单体偶氮食品颜色（如酒石黄）相当出色，可作为本身适合使用的酸不溶性颜料湖的成分。 在食物。
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公开(公告)号：US4233328A
公开(公告)日：1980-11-11
申请号：US948465
申请日：1978-10-04
摘要： A group of water-soluble polymeric yellow colors and their preparation is disclosed. These colors comprise a plurality of units of a chromophore of the formula ##STR1## wherein M.sup.+ is a pharmaceutically acceptable monovalent cation, attached directly to amine units present in a nonchromophoric polymer backbone. In a preferred embodiment of the invention the backbone is a homopolymer or copolymer of vinylamine. These colorants find special utility as nonabsorbable colorants for edibles, especially foods and beverages, where their yellow hue is an excellent color match for existing monomeric azo food colors such as tartrazine, and as components of acid-insoluble pigment lakes which are themselves suitable for use in edibles.
摘要翻译： 公开了一组水溶性聚合黄色及其制备方法。 这些颜色包括多个单位的式“IMAGE”的发色团，其中M +是药学上可接受的一价阳离子，其直接连接在存在于非着色聚合物主链中的胺单元上。 在本发明的优选实施方案中，主链是乙烯基胺的均聚物或共聚物。 这些着色剂特别适用于食品，特别是食品和饮料的非吸收性着色剂，其中黄色色调与现有的单体偶氮食品颜色（如酒石黄）相当出色，可作为本身适合使用的酸不溶性颜料湖的成分。 在食物。
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4.发明授权Oil soluble polymeric antioxidant prepared by condensation of divinylbenzene, hydroxyanisole, tertiary butyl hydroquinone, tertiary butyl phenol and bisphenol A under ortho alkylation conditions 失效通过二乙烯基苯，羟基苯甲醚，叔丁基氢醌，叔丁基苯酚和双酚A在邻位烷基化条件下缩合制备的油溶性聚合物抗氧化剂
公开(公告)号：US3996199A
公开(公告)日：1976-12-07
申请号：US658943
申请日：1976-02-17
IPC分类号： A23L3/3463 , C08G61/02 , C08L101/00 , C09K15/08 , C08K5/13
CPC分类号： A23L3/3463 , C08G61/02 , C08L101/00 , C09K15/08 , C08G2261/3424
摘要： Phenolic polymers formed by the reaction of divinylbenzene with a mixture of hydroxyanisole, tertiary butylhydroquinone, tertiary butyl phenol and bisphenol A (and optionally para-cresol) under condensation conditions in the presence of a phenol ortho alkylation catalyst are disclosed. These materials find use as oil-soluble antioxidants especially for edibles.
摘要翻译： 公开了在苯酚正烷基化催化剂存在下，在缩合条件下二乙烯基苯与羟基苯甲醚，叔丁基氢醌，叔丁基苯酚和双酚A（和任选的对甲酚）的混合物反应形成的酚醛聚合物。 这些材料可用作油溶性抗氧化剂，特别适用于食品。
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公开(公告)号：US5670643A
公开(公告)日：1997-09-23
申请号：US405559
申请日：1995-03-16
申请人： Roman Davis , Alan Millar
发明人： Roman Davis , Alan Millar
IPC分类号： C07J73/00 , C07D221/18
CPC分类号： C07J73/005
摘要： The present invention relates to a process for the preparation of finasteride, the compound of formula (I), comprising the reaction of the compound of formula (II) with t-butylamine. ##STR1##
摘要翻译： 本发明涉及制备非那雄胺的方法，式（I）化合物包括式（II）化合物与叔丁胺的反应。
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公开(公告)号：US4889866A
公开(公告)日：1989-12-26
申请号：US61752
申请日：1987-06-11
申请人： Jurg R. Pfister , Roman Davis , Chi-Ho Lee
发明人： Jurg R. Pfister , Roman Davis , Chi-Ho Lee
IPC分类号： C07D211/90
CPC分类号： C07D211/90
摘要： Novel arylsulfonyl-dihydropyridine derivatives which are useful as calcium entry-blocker cardiovascular agents have the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.1 is hydrogen, lower alkyl, or lower alkoxyalkyl;R.sup.2 is hydrogen or chloro; andR.sup.3 is hydrogen, lower alkyl, or lower alkoxyethyl.A novel process using chiral sulfoxide reagents efficiently produces single isomers of these and other sulfonyl dihydropyridines.
摘要翻译： 可用作钙进入阻断剂心血管药的新型芳基磺酰基 - 二氢吡啶衍生物具有下式：其中R 1是氢，低级烷基或低级烷氧基烷基; R2是氢或氯; 和R3是氢，低级烷基或低级烷氧基乙基。 使用手性亚砜试剂的新方法有效地产生了这些和其他磺酰二氢吡啶的单一异构体。
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