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公开(公告)号:US20120232005A1
公开(公告)日:2012-09-13
申请号:US13367237
申请日:2012-02-06
Applicant: Jean-Louis Dasseux , Daniela Carmen Oniciu , Rose Ackermann
Inventor: Jean-Louis Dasseux , Daniela Carmen Oniciu , Rose Ackermann
CPC classification number: A61K38/1709 , A61K38/17 , A61K38/18 , A61K45/00 , A61K47/50 , C07K1/04 , C07K1/042 , C07K14/775 , Y10T428/2982
Abstract: The present disclosure relates to lipoprotein complexes and lipoprotein populations and their use in the treatment and/or prevention of dyslipidemic diseases, disorders, and/or conditions. The disclosure further relates to recombinant expression of apolipoproteins, purification of apolipoproteins, and production of lipoprotein complexes using thermal cycling-based methods.
Abstract translation: 本公开涉及脂蛋白复合物和脂蛋白种群及其在治疗和/或预防血脂异常疾病,病症和/或病症中的用途。 本公开还涉及载脂蛋白的重组表达,载脂蛋白的纯化,以及使用基于热循环的方法产生脂蛋白复合物。