公开(公告)号：US5780623A

公开(公告)日：1998-07-14

申请号：US605883

申请日：1996-02-23

申请人： Rudolf P.M. Guit ,  Samuel L. Lane ,  Wim Buijs

发明人： Rudolf P.M. Guit ,  Samuel L. Lane ,  Wim Buijs

IPC分类号： C07D201/08

CPC分类号： C07D201/08

摘要： Process to prepare .epsilon.-caprolactam starting from a liquid aqueous mixture containing an alcohol and 6-aminocaproic acid by cyclization of 6-aminocaproic acid in the aqueous mixture at an elevated temperature. The alcohol is separated from the starting aqueous mixture before performing the cyclization to such extent that the concentration of alcohol in the aqueous mixture during the cyclization is less than 1 wt. %. The advantages include reduced amounts of undesirable by-product.