摘要:
The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment of a FAK and/or Pyk2 mediated disorder or disease.
摘要:
Mechanisms for performing database queries are provided. With these mechanisms, in response to a query request, a query plan intended for minimum query response time and a query plan intended for minimum query total time for the query request are obtained execution of the minimum query response time query plan and the minimum query total time query plan is started. Before the execution of the minimum query total time query plan reaches a specified point, an initial query result obtained from the execution of the minimum query response time query plan is output. In response to the execution of the minimum query total time query plan reaching the specified point, continuing the execution of the minimum query total time query plan to output remaining query results.
摘要:
The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment of a FAK and/or Pyk2 mediated disorder or disease.
摘要:
Dynamic features are utilized with CRFs to handle long-distance dependencies of output labels. The dynamic features present a probability distribution involved in explicit distance from/to a special output label that is pre-defined according to each application scenario. Besides the number of units in the segment (from the previous special output label to the current unit), the dynamic features may also include the sum of any basic features of units in the segment. Since the added dynamic features are involved in the distance from the previous specific label, the searching lattice associated with Viterbi searching is expanded to distinguish the nodes with various distances. The dynamic features may be used in a variety of different applications, such as Natural Language Processing, Text-To-Speech and Automatic Speech Recognition. For example, the dynamic features may be used to assist in prosodic break and pause prediction.
摘要:
A method for joining tables in multiple heterogeneous distributed databases implemented by at least two data sources accessible to a federal database server over a network includes: transmitting from the federated database server a sub-command to a first of the data sources responsive to the federated database server receiving a data query; retrieving, with the federated database server, block data from the first data source related to the data query using block fetching according to the sub-command; transmitting, with the federated database server, at least a portion of the block data to a second of the data sources together with an instruction for the second data source to perform a join operation on the portion of the block data and a data table stored by the second data source related to the query; and retrieving a result of the join operation with the federated database server.
摘要:
A mobile station includes an RF transceiver and a user interface. The mobile station further includes a plurality of data processor cores each having a first interface supporting a first bus coupled to an associated one of a plurality of program memories, a second interface supporting a second bus coupled to a common data memory, and a third interface supporting a third bus coupled to at least one input/output device. Each of the first, second and third buses include an address bus that is sourced from the processor core and a data bus. The plurality of data processor cores may be contained within a single integrated circuit package, such as an ASIC, in a System on Chip (SoC) configuration. In this case a first processor core may function as a CPU for controlling the overall operation of the mobile station, including the user interface, while a second processor core functions as a DSP for controlling operation of the RF transceiver. The first interface supports a unidirectional data bus from the program memory, and the second interface and the third interface each support a bidirectional data bus. Each of the plurality of processor cores has the second interface coupled to the common data memory through a common memory control unit, and the third interface is coupled to at least one of a plurality of interface devices through a common control bus unit. Each of the processor cores operates with a clock signal and fetches an instruction from the associated one of the plurality of program memories using the address bus and the data bus of the first interface, the instruction fetch being referenced to a predetermined edge of the clock signal. Each processor core then begins an execution of the fetched instruction on a next occurrence of said predetermined edge of said clock signal. The first interface is responsive to an assertion of a HOLD signal for suspending the fetching of a next instruction from the program memory. The segregation of the program, data and control buses provides for increased efficiencies and bus bandwidth, increasing the number of instructions that are executed per unit of time at a given clock frequency.
摘要:
An apparatus and method for prioritizing interrupt requests in a RISC processor. By utilizing hardware to prioritize the requests, processor time is reduced. The acknowledge signal from a priority resolve circuit selects the given service routine entry to branch instruction generating circuit. A lower priority service routine can be interrupted by a higher priority request.
摘要:
A spontaneous-extending and anti-rotation scoliosis correcting system comprises pedicle screws and a plurality of correcting rods locked with the pedicle screws. Each correcting rod includes at least one sleeve and at least one inserting rod which can be inserted into the sleeve. The inner wall of the sleeve and the inserting rod are the same in shape and are in clearance fit. A positioning mechanism for restricting the relative rotation of the inserting rod with respect to the sleeve is arranged on a matching surface between the inserting rod and the sleeve. The scoliosis correcting system has the benefits of ensuring the lateral stability and the anti-rotation function for scoliosis correction; having the performance of spontaneous extending along the growth direction of the spine; and ensuring both the short-term operating effect and the long-term curative effect.
摘要:
Aspects of the disclosure relate to location sensing based at least on magnetic measurements within an environment. In certain aspects, the location sensing contemplates several environment and/or operational conditions of an electronic device that conducts the sensing, including soft iron variations, motion characteristic of the device, and/or the elevation of the device. In other aspects, magnetic mappings for the environment can be generated in accordance with one or more of such conditions, and accurate location sensing can be achieved based at least on such mappings and magnetic measurements at a location of the device within the environment.
摘要:
A text-to-speech (TTS) engine combines recorded speech with synthesized speech from a TTS synthesizer based on text input. The TTS engine receives the text input and identifies the domain for the speech (e.g. navigation, dialing, . . . ). The identified domain is used in selecting domain specific speech recordings (e.g. pre-recorded static phrases such as “turn left”, “turn right” . . . ) from the input text. The speech recordings are obtained based on the static phrases for the domain that are identified from the input text. The TTS engine blends the static phrases with the TTS output to smooth the acoustic trajectory of the input text. The prosody of the static phrases is used to create similar prosody in the TTS output.