摘要:
The present disclosure relates to an installation (10) that includes a floating top structure (20) and a fully submerged bottom structure (22). The top structure is mobile between a production position and an evacuation position. The installation (10) retains the top structure (20) in its production position which includes at least one rigid rod (90) carried by the top structure (20), at least one rod abutment (92) carried by the rigid rod (90) in the vicinity of its lower end and at least one complementary abutment (94) secured to a base (60) of the bottom structure (22). Each rod abutment (92) and each complementary abutment (94) are mobile in rotation relative to one another between an engaged configuration in which urging of the rigid rod (90) towards its top position (20) retains the top structure in its production position, and a disengaged configuration releasing the top structure (20) from the bottom structure (22).
摘要:
Provided herein are methods for selecting and treating a subject with leukemia, wherein the subject is selected for treatment and is treated with an MDM2 inhibitor because said subject's cells contain an FLT3-ITD mutation.
摘要:
The present disclosure relates to an installation (10) that includes a floating top structure (20) and a fully submerged bottom structure (22). The top structure is mobile between a production position and an evacuation position. The installation (10) retains the top structure (20) in its production position which includes at least one rigid rod (90) carried by the top structure (20), at least one rod abutment (92) carried by the rigid rod (90) in the vicinity of its lower end and at least one complementary abutment (94) secured to a base (60) of the bottom structure (22). Each rod abutment (92) and each complementary abutment (94) are mobile in rotation relative to one another between an engaged configuration in which urging of the rigid rod (90) towards its top position (20) retains the top structure in its production position, and a disengaged configuration releasing the top structure (20) from the bottom structure (22).