公开(公告)号：US07402382B2

公开(公告)日：2008-07-22

申请号：US10481943

申请日：2002-06-24

申请人： Jose Carlos Zapata Babio ,  Santiago Rodriguez Lopez

发明人： Jose Carlos Zapata Babio ,  Santiago Rodriguez Lopez

IPC分类号： C12Q1/68 ,  C12P19/34

CPC分类号： C12Q1/6827 ,  C12Q2531/113 ,  C12Q2537/107 ,  C12Q2565/125

摘要： Method GEDAP (Genotyping Based on Diagnostic Amplification Products) for detecting and/or preventing genotyping errors on the basis of the amplification products of a polymorphic locus. The method is based on the joint analysis of homoduplexes and Diagnostic Additional Products (DAPs) generated from the amplification of a polymorphic locus. The method is highly effective for detecting and/or preventing genotyping errors due to total or partial non-amplifications occurring during amplification procedures such as the Polymerase Chain Reaction (PCR).

摘要翻译： 方法GEDAP（基于诊断扩增产物的基因分型），用于基于多态性位点的扩增产物检测和/或预防基因分型错误。 该方法基于通过扩增多态性位点产生的同源双链体和诊断性附加产物（DAP）的联合分析。 该方法对于检测和/或预防由于在扩增过程（例如聚合酶链式反应（PCR））期间发生的全部或部分非扩增而导致的基因分型错误是非常有效的。