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公开(公告)号：US20160296533A1
公开(公告)日：2016-10-13
申请号：US15037399
申请日：2014-11-20
发明人： Scott Freeman
IPC分类号： A61K31/565 , A61K9/00
CPC分类号： A61K31/565 , A61K9/0019 , A61K9/0053 , A61K45/06 , C07J1/007 , C07J15/00 , A61K2300/00
摘要： A composition for enhancing libido of a pharmaceutically effective amount of a libido-enhancing therapeutic of (5S,10R,13S,17S)-13-methyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17yl acetate (Formula I), (3S,5S,10R,13S,17S)-3-hydroxy-13-methylhexadecahydro-1H-cyclopenta[a]phenanthren-17yl acetate (Formula II), (5S,10S,13S,17S)-17-hydroxy-13-methyltetradecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Formula III), isomers thereof, analogs thereof, or combinations thereof, and a pharmaceutically acceptable carrier. A method of enhancing libido, by administering the composition to an individual in need of an enhanced libido, and enhancing libido in the individual or animal which is male or female. A method of enhancing libido, by administering the composition of the present invention to an individual at an age when libido and sexual desire have naturally decreased, and enhancing libido in the individual. A composition for enhancing libido and arousal, including a pharmaceutically effective amount of a libido-enhancing therapeutic in combination with a sexual dysfunction therapeutic. A method of enhancing libido and arousal.
摘要翻译： （5S，10R，13S，17S）-13-甲基-3-氧代十六氢-1H-环戊二烯并[a]菲-1,17-乙酸酯（式I）的药学有效量的性欲增强治疗剂的性欲组合物， （3S，5S，10R，13S，17S）-3-羟基-13-甲基十六氢-1H-环戊二烯并[a]菲-1,17-乙酸酯（式II），（5S，10S，13S，17S）-17-羟基-13 - 甲基十四氢-1H-环戊二烯并[a]菲-3（2H） - 酮（式III），其异构体，其类似物或其组合，和药学上可接受的载体。 通过将该组合物施用于需要增强性欲的个体和增强男性或女性个体或动物中的性欲的方法来增强性欲。 通过在性欲和性欲自然降低的年龄向个体施用本发明的组合物并增强个人的性欲的方法来增强性欲。 一种用于增强性欲和兴奋的组合物，包括药物有效量的与性功能障碍治疗组合的性欲增强治疗剂。 增强性欲和唤醒的方法。
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公开(公告)号：US09855281B2
公开(公告)日：2018-01-02
申请号：US15037399
申请日：2014-11-20
发明人： Scott Freeman
CPC分类号： A61K31/565 , A61K9/0019 , A61K9/0053 , A61K45/06 , C07J1/007 , C07J15/00 , A61K2300/00
摘要： A composition for enhancing libido of a pharmaceutically effective amount of a libido-enhancing therapeutic of (5S,10R,13S,17S)-13-methyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17yl acetate (Formula I), (3S,5S,10R,13S,17S)-3-hydroxy-13-methylhexadecahydro-1H-cyclopenta[a]phenanthren-17yl acetate (Formula II), (5S,10S,13S,17S)-17-hydroxy-13-methyltetradecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Formula III), isomers thereof, analogs thereof, or combinations thereof, and a pharmaceutically acceptable carrier. A method of enhancing libido, by administering the composition to an individual in need of an enhanced libido, and enhancing libido in the individual or animal which is male or female. A method of enhancing libido, by administering the composition of the present invention to an individual at an age when libido and sexual desire have naturally decreased, and enhancing libido in the individual. A composition for enhancing libido and arousal, including a pharmaceutically effective amount of a libido-enhancing therapeutic in combination with a sexual dysfunction therapeutic. A method of enhancing libido and arousal.
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